Left ventricular mass and left ventricular mass index in normal malay primary school children.

Left ventricular mass (LVM) and Left ventricular mass Index (LVMI) are two parameters that are considered important in predicting the outcomes of cardiovascular diseases in adults. Even though there are a lot of interest in the problem of left ventricular hypertrophy in children,there is relatively...

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Main Author: Mat Arifin, Fazila
Format: Thesis
Language:English
Published: 2012
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Online Access:http://eprints.usm.my/60982/1/DR%20FAZILA%20BINTI%20MAT%20ARIFIN%20-%20e.pdf
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spelling my-usm-ep.609822024-11-20T03:29:50Z Left ventricular mass and left ventricular mass index in normal malay primary school children. 2012 Mat Arifin, Fazila R Medicine (General) RJ101 Child Health. Child health services RJ370-550 Diseases of children and adolescents Left ventricular mass (LVM) and Left ventricular mass Index (LVMI) are two parameters that are considered important in predicting the outcomes of cardiovascular diseases in adults. Even though there are a lot of interest in the problem of left ventricular hypertrophy in children,there is relatively little published data on normal values of the left ventricular mass (LVM) during the developmental age. A cross sectional study was conducted from October to November, 2009 at Sekolah Kebangsaan Lundang, Kota Bharu. Normal primary school children from preschool, Standard 2, 4 and 6 were included in this study. Children with history of heart problem or hypertension, abnormal physical examination or echocardiogram findings and abnormal BMI were excluded. A set of questionnaires and consent were obtained from parents prior to the examination. Physical examination, weight, height, blood pressure and echocardiogram measurements were recorded. LVM measurement was calculated by echocardiogram machine and LVMI was calculated by dividing LVM to height in meter power of 2.7 (LVM/height2'). Percentile charts were created from the data available according to age, weight, height. BSA and BMI. The factors affecting LVM and LVMI were identified using simple linear regression (SLR). Multiple linear regressions (MLR)was performed to determine the final model affecting LVM and LVMI. The most acceptable percentile chart in our study was percentile chart according to age. Factors affecting LVM were age, weight, height, BMI, BSA and SBP. While factors affecting LVMI were age, weight, height and BSA. Echocardiogram measurements found that aortic root, aortic arch and MV annulus affect LVM, whereas aortic root (annulus), aortic arch, Left atrium and MV annulus affect LVMI. From multiple linear regressions, we identified that weight and SBP had strong correlation with LVM while age, SBP and height had strong correlation with LVMI. We have provided a pilot percentile chart for LVM and LVMI of normal school children between aged 5 to 12 years old but larger sample size would be able to produce a better percentile chart. LVM was most affected by weight and SBP whereas LVMI were affected by age, SBP and height. We provided a formula to estimate the LVM (r2=0.24) and LVMI (r2= 0.40) with standard error of 22.97 and 13.74. The formula as below: LVM (g) = -6.81 + I.05(weight in kg) + 0.42(SBP in mmHg) LVMI = 94.23+1.87(age in years) -80.32(height in meters) +0.26(SBP in mmHg) 2012 Thesis http://eprints.usm.my/60982/ http://eprints.usm.my/60982/1/DR%20FAZILA%20BINTI%20MAT%20ARIFIN%20-%20e.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic R Medicine (General)
R Medicine (General)
RJ370-550 Diseases of children and adolescents
spellingShingle R Medicine (General)
R Medicine (General)
RJ370-550 Diseases of children and adolescents
Mat Arifin, Fazila
Left ventricular mass and left ventricular mass index in normal malay primary school children.
description Left ventricular mass (LVM) and Left ventricular mass Index (LVMI) are two parameters that are considered important in predicting the outcomes of cardiovascular diseases in adults. Even though there are a lot of interest in the problem of left ventricular hypertrophy in children,there is relatively little published data on normal values of the left ventricular mass (LVM) during the developmental age. A cross sectional study was conducted from October to November, 2009 at Sekolah Kebangsaan Lundang, Kota Bharu. Normal primary school children from preschool, Standard 2, 4 and 6 were included in this study. Children with history of heart problem or hypertension, abnormal physical examination or echocardiogram findings and abnormal BMI were excluded. A set of questionnaires and consent were obtained from parents prior to the examination. Physical examination, weight, height, blood pressure and echocardiogram measurements were recorded. LVM measurement was calculated by echocardiogram machine and LVMI was calculated by dividing LVM to height in meter power of 2.7 (LVM/height2'). Percentile charts were created from the data available according to age, weight, height. BSA and BMI. The factors affecting LVM and LVMI were identified using simple linear regression (SLR). Multiple linear regressions (MLR)was performed to determine the final model affecting LVM and LVMI. The most acceptable percentile chart in our study was percentile chart according to age. Factors affecting LVM were age, weight, height, BMI, BSA and SBP. While factors affecting LVMI were age, weight, height and BSA. Echocardiogram measurements found that aortic root, aortic arch and MV annulus affect LVM, whereas aortic root (annulus), aortic arch, Left atrium and MV annulus affect LVMI. From multiple linear regressions, we identified that weight and SBP had strong correlation with LVM while age, SBP and height had strong correlation with LVMI. We have provided a pilot percentile chart for LVM and LVMI of normal school children between aged 5 to 12 years old but larger sample size would be able to produce a better percentile chart. LVM was most affected by weight and SBP whereas LVMI were affected by age, SBP and height. We provided a formula to estimate the LVM (r2=0.24) and LVMI (r2= 0.40) with standard error of 22.97 and 13.74. The formula as below: LVM (g) = -6.81 + I.05(weight in kg) + 0.42(SBP in mmHg) LVMI = 94.23+1.87(age in years) -80.32(height in meters) +0.26(SBP in mmHg)
format Thesis
qualification_level Master's degree
author Mat Arifin, Fazila
author_facet Mat Arifin, Fazila
author_sort Mat Arifin, Fazila
title Left ventricular mass and left ventricular mass index in normal malay primary school children.
title_short Left ventricular mass and left ventricular mass index in normal malay primary school children.
title_full Left ventricular mass and left ventricular mass index in normal malay primary school children.
title_fullStr Left ventricular mass and left ventricular mass index in normal malay primary school children.
title_full_unstemmed Left ventricular mass and left ventricular mass index in normal malay primary school children.
title_sort left ventricular mass and left ventricular mass index in normal malay primary school children.
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Perubatan
publishDate 2012
url http://eprints.usm.my/60982/1/DR%20FAZILA%20BINTI%20MAT%20ARIFIN%20-%20e.pdf
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