Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering

Surgical restoration of extensive tracheal lesions is complicated, and it necessitates the use of a biocompatible, mechanically stable, and non-toxic material that degrades gradually to overcome the limitation of allografts. A three-dimensional (3D) printed tracheal scaffold produced from polymers i...

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Main Author:	Samat, Asmak Abdul
Format:	Thesis
Language:	English
Published:	2023
Subjects:	R5-920 Medicine (General)
Online Access:	http://eprints.usm.my/61260/1/24%20Pages%20from%20ASMAK%20BINTI%20ABDUL%20SAMAT.pdf
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id	my-usm-ep.61260
record_format	uketd_dc
spelling	my-usm-ep.612602024-10-10T03:33:41Z Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering 2023-02 Samat, Asmak Abdul R5-920 Medicine (General) Surgical restoration of extensive tracheal lesions is complicated, and it necessitates the use of a biocompatible, mechanically stable, and non-toxic material that degrades gradually to overcome the limitation of allografts. A three-dimensional (3D) printed tracheal scaffold produced from polymers is one option for addressing some of the challenges in tracheal transplantation. Polymer blending is one approach for creating material with specific properties for a trachea scaffold. The goal of this study was to evaluate the physical, mechanical, and biological properties of thermoplastic polyurethane (TPU) and polylactic acid (PLA) blend as prospective tracheal replacement materials. Both materials are well-known for their promising properties when utilised independently, thus broadly employed in various applications, especially in the biomedical field. It is hypothesised that combining the two materials and the subsequent 3D printing method produces a composite with suitable qualities for tracheal replacement. Different TPU and PLA compositions were melt-blended and characterised for their physical and mechanical properties, 2023-02 Thesis http://eprints.usm.my/61260/ http://eprints.usm.my/61260/1/24%20Pages%20from%20ASMAK%20BINTI%20ABDUL%20SAMAT.pdf application/pdf en public phd doctoral Perpustakaan Hamzah Sendut Institut Perubatan & Pergigian Termaju
institution	Universiti Sains Malaysia
collection	USM Institutional Repository
language	English
topic	R5-920 Medicine (General)
spellingShingle	R5-920 Medicine (General) Samat, Asmak Abdul Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
description	Surgical restoration of extensive tracheal lesions is complicated, and it necessitates the use of a biocompatible, mechanically stable, and non-toxic material that degrades gradually to overcome the limitation of allografts. A three-dimensional (3D) printed tracheal scaffold produced from polymers is one option for addressing some of the challenges in tracheal transplantation. Polymer blending is one approach for creating material with specific properties for a trachea scaffold. The goal of this study was to evaluate the physical, mechanical, and biological properties of thermoplastic polyurethane (TPU) and polylactic acid (PLA) blend as prospective tracheal replacement materials. Both materials are well-known for their promising properties when utilised independently, thus broadly employed in various applications, especially in the biomedical field. It is hypothesised that combining the two materials and the subsequent 3D printing method produces a composite with suitable qualities for tracheal replacement. Different TPU and PLA compositions were melt-blended and characterised for their physical and mechanical properties,
format	Thesis
qualification_name	Doctor of Philosophy (PhD.)
qualification_level	Doctorate
author	Samat, Asmak Abdul
author_facet	Samat, Asmak Abdul
author_sort	Samat, Asmak Abdul
title	Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_short	Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_full	Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_fullStr	Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_full_unstemmed	Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering
title_sort	physico-mechanical and biological evaluation of three-dimensional printed thermoplastic polyurethane and polylactic acid scaffold for tracheal tissue engineering
granting_institution	Perpustakaan Hamzah Sendut
granting_department	Institut Perubatan & Pergigian Termaju
publishDate	2023
url	http://eprints.usm.my/61260/1/24%20Pages%20from%20ASMAK%20BINTI%20ABDUL%20SAMAT.pdf
_version_	1818647380395819008

Physico-Mechanical And Biological Evaluation Of Three-Dimensional Printed Thermoplastic Polyurethane And Polylactic Acid Scaffold For Tracheal Tissue Engineering

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