Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor

Sarcopenia is a condition characterized by loss of skeletal muscle mass and function. Although it is primarily a disease of the elderly, its development may be associated with conditions that are not exclusively seen in elderly population. Hence, it is important to identify the prevalence of sarcope...

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Main Author: Moorthy, Shantasaroopini Sathia
Format: Thesis
Language:English
Published: 2023
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Online Access:http://eprints.usm.my/61330/1/24%20Pages%20from%20SHANTASAROOPINI%20AP%20SATHIA%20MOORTHY.pdf
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spelling my-usm-ep.613302024-10-18T00:56:26Z Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor 2023-09 Moorthy, Shantasaroopini Sathia RS1-441 Pharmacy and materia medica Sarcopenia is a condition characterized by loss of skeletal muscle mass and function. Although it is primarily a disease of the elderly, its development may be associated with conditions that are not exclusively seen in elderly population. Hence, it is important to identify the prevalence of sarcopenia in chronic kidney disease population and its associated risk factors in pre-dialysis patients with chronic kidney disease. This eight months cross-sectional study was conducted on 250 pre-dialysis patients with chronic kidney disease aged 18 years or older who attended the out-patient Renal Clinic at Hospital Pakar Sultanah Fatimah Muar Johor. By using the diagnostic methods proposed by AWGS, sarcopenia was detected in 5.2% of pre-dialysis patients with CKD, with CKD stage 3-5 accounting for 0.4%, 0.8%, and 4% respectively. Multiple logistic regression models revealed that sarcopenia was associated with age (AOR: 0.966, 95% CI: 0.801-1.164), body mass index (BMI) (AOR: 0.390, 95% CI: 0.166-0.912), presence of chronic illness (AOR: 0.529, 95% CI: 0.023-12.237), MBI score (AOR: 0.644, 95% CI: 0.470-0.884, and serum albumin (AOR: 0.813, 95% CI: 0.526-1.257). 2023-09 Thesis http://eprints.usm.my/61330/ http://eprints.usm.my/61330/1/24%20Pages%20from%20SHANTASAROOPINI%20AP%20SATHIA%20MOORTHY.pdf application/pdf en public masters Perpustakaan Hamzah Sendut Pusat Pengajian Sains Farmasi
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Moorthy, Shantasaroopini Sathia
Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
description Sarcopenia is a condition characterized by loss of skeletal muscle mass and function. Although it is primarily a disease of the elderly, its development may be associated with conditions that are not exclusively seen in elderly population. Hence, it is important to identify the prevalence of sarcopenia in chronic kidney disease population and its associated risk factors in pre-dialysis patients with chronic kidney disease. This eight months cross-sectional study was conducted on 250 pre-dialysis patients with chronic kidney disease aged 18 years or older who attended the out-patient Renal Clinic at Hospital Pakar Sultanah Fatimah Muar Johor. By using the diagnostic methods proposed by AWGS, sarcopenia was detected in 5.2% of pre-dialysis patients with CKD, with CKD stage 3-5 accounting for 0.4%, 0.8%, and 4% respectively. Multiple logistic regression models revealed that sarcopenia was associated with age (AOR: 0.966, 95% CI: 0.801-1.164), body mass index (BMI) (AOR: 0.390, 95% CI: 0.166-0.912), presence of chronic illness (AOR: 0.529, 95% CI: 0.023-12.237), MBI score (AOR: 0.644, 95% CI: 0.470-0.884, and serum albumin (AOR: 0.813, 95% CI: 0.526-1.257).
format Thesis
qualification_level Master's degree
author Moorthy, Shantasaroopini Sathia
author_facet Moorthy, Shantasaroopini Sathia
author_sort Moorthy, Shantasaroopini Sathia
title Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_short Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_full Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_fullStr Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_full_unstemmed Prevalence And Factors Associated With Sarcopenia In Outpatient Pre-Dialysis Patients In A Tertiary Care Centre In Johor
title_sort prevalence and factors associated with sarcopenia in outpatient pre-dialysis patients in a tertiary care centre in johor
granting_institution Perpustakaan Hamzah Sendut
granting_department Pusat Pengajian Sains Farmasi
publishDate 2023
url http://eprints.usm.my/61330/1/24%20Pages%20from%20SHANTASAROOPINI%20AP%20SATHIA%20MOORTHY.pdf
_version_ 1818647397018894336