Evaluation of high-dose rate (HDR) radiobiologic dose-equivalent web tool for cervical cancer

Following successful precision and timing accuracy phases, the next step is a comprehensive evaluation of the web application versus the Microsoft Excel template. Testing with clinical data ensures robustness. Documentation and training for medical physicists are essential. Implementation will start...

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Bibliographic Details
Main Author: Shafizan, Haziq Asyraaf
Format: Thesis
Language:English
Published: 2024
Subjects:
Online Access:http://eprints.usm.my/61333/1/Haziq%20Asyraaf%20Shafizan-E.pdf
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Summary:Following successful precision and timing accuracy phases, the next step is a comprehensive evaluation of the web application versus the Microsoft Excel template. Testing with clinical data ensures robustness. Documentation and training for medical physicists are essential. Implementation will start with a pilot group, followed by full-scale deployment. Evaluation of BED and EQD2 values reveals minimal deviations, indicating high comparability. For target tissue, BED deviation is 0.048% and EQD2 is 0.008%. The bladder shows a BED deviation of 0.055% and EQD2 of 0.073%. The rectum has a BED deviation of 0.014% and EQD2 of 0.029%. For the sigmoid, the BED deviation is 0.035% and EQD2 is 0.142%. All deviations are within the 3% tolerance limit. The web application completes the full treatment in 138.69 seconds, compared to 202.67 seconds for Excel, with a TER of 1.46. For the first additional patient, the web application takes 96.84 seconds, while Excel takes 107.11 seconds, giving a TER of 1.11. For the second additional patient, the web application takes 94.77 seconds versus 78.66 seconds for Excel, with a TER of 0.83. Despite occasional exceptions, the web application is generally more time-efficient and reliable.