Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb].

Although the use of chemotherapy has evolved remarkably during the past 30 years for treatment in leukemia patients, it remains a difficult disease to treat where the main problem is drug resistance. This is due to over expression of multi-drug resistance gene (MDR1) and it’s over expression has bee...

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Main Author: Yahaya, Badrul Hisham
Format: Thesis
Language:English
Published: 2006
Subjects:
Online Access:http://eprints.usm.my/8626/1/DEVELOPMENT_OF_DENATURING_HIGH_PERFORMANCE_LIQUID_CHROMATOGRAPHY_%28dHPLC%29_IN_DETECTION_OF_COMMON_POLYMORPHISMS_IN_THE_MULTI-DRUG_RESISTANCE_%28MDR1%29_GENE_IN_MALAY_PATIENTS_WITH_LEUKEMIA.pdf
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spelling my-usm-ep.86262017-08-30T01:57:43Z Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb]. 2006 Yahaya, Badrul Hisham QH301 Biology Although the use of chemotherapy has evolved remarkably during the past 30 years for treatment in leukemia patients, it remains a difficult disease to treat where the main problem is drug resistance. This is due to over expression of multi-drug resistance gene (MDR1) and it’s over expression has been described in many tumors resistant to cytotoxic drugs including leukemias. Walaupun keberkesanan penggunaan kemoterapi dalam rawatan terhadap pesakit leukimia adalah jelas terbukti, namun leukimia tetap merupakan penyakit yang sukar dirawat terutamanya dalam masalah kerintangan pesakit terhadap ubat-ubatan (dadah). 2006 Thesis http://eprints.usm.my/8626/ http://eprints.usm.my/8626/1/DEVELOPMENT_OF_DENATURING_HIGH_PERFORMANCE_LIQUID_CHROMATOGRAPHY_%28dHPLC%29_IN_DETECTION_OF_COMMON_POLYMORPHISMS_IN_THE_MULTI-DRUG_RESISTANCE_%28MDR1%29_GENE_IN_MALAY_PATIENTS_WITH_LEUKEMIA.pdf application/pdf en public masters Universiti Sains Malaysia. Pusat Pengajian Sains Perubatan
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic QH301 Biology
spellingShingle QH301 Biology
Yahaya, Badrul Hisham
Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb].
description Although the use of chemotherapy has evolved remarkably during the past 30 years for treatment in leukemia patients, it remains a difficult disease to treat where the main problem is drug resistance. This is due to over expression of multi-drug resistance gene (MDR1) and it’s over expression has been described in many tumors resistant to cytotoxic drugs including leukemias. Walaupun keberkesanan penggunaan kemoterapi dalam rawatan terhadap pesakit leukimia adalah jelas terbukti, namun leukimia tetap merupakan penyakit yang sukar dirawat terutamanya dalam masalah kerintangan pesakit terhadap ubat-ubatan (dadah).
format Thesis
qualification_level Master's degree
author Yahaya, Badrul Hisham
author_facet Yahaya, Badrul Hisham
author_sort Yahaya, Badrul Hisham
title Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb].
title_short Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb].
title_full Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb].
title_fullStr Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb].
title_full_unstemmed Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb].
title_sort development of denaturing high performance liquid chromatography (dhplc) in detection of common polymorphisms in the multi-drug resistance (mdr1) gene among malay patients with leukemia [qh324.9.l5 b138 2006 f rb].
granting_institution Universiti Sains Malaysia.
granting_department Pusat Pengajian Sains Perubatan
publishDate 2006
url http://eprints.usm.my/8626/1/DEVELOPMENT_OF_DENATURING_HIGH_PERFORMANCE_LIQUID_CHROMATOGRAPHY_%28dHPLC%29_IN_DETECTION_OF_COMMON_POLYMORPHISMS_IN_THE_MULTI-DRUG_RESISTANCE_%28MDR1%29_GENE_IN_MALAY_PATIENTS_WITH_LEUKEMIA.pdf
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