Investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [RS199.5. M211 2007 f rb].

Dua drug model yang termasuk dalam dua kumpulan Biopharmaceutics Classification System (BCS) yang berbeza, iaitu vancomycin (VCM), satu sebatian kelas III (keterlarutan tinggi dan ketelapan rendah), dan griseofulvin, satu drug kelas II (keterlarutan rendah and ketelapan tinggi) telah digunakan untuk...

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Main Author: Magosso, Enrico
Format: Thesis
Language:English
Published: 2007
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Online Access:http://eprints.usm.my/9691/1/INVESTIGATION_OF_THE_POTENTIAL_OF_GELUCIRE_44_14_FOR_ENHANCING_ORAL_BIOAVAILABILITY_USING_TWO_MODEL_DRUGS.pdf
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spelling my-usm-ep.96912017-03-22T01:59:53Z Investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [RS199.5. M211 2007 f rb]. 2007-03 Magosso, Enrico RS1-441 Pharmacy and materia medica Dua drug model yang termasuk dalam dua kumpulan Biopharmaceutics Classification System (BCS) yang berbeza, iaitu vancomycin (VCM), satu sebatian kelas III (keterlarutan tinggi dan ketelapan rendah), dan griseofulvin, satu drug kelas II (keterlarutan rendah and ketelapan tinggi) telah digunakan untuk menilai potensi satu pembawa gliserida berpoliglikol, iaitu Gelucire 44/14, untuk meningkatkan biokeperolehan oral. Two model drugs belonging to different groups of the Biopharmaceutics Classification System (BCS), which are vancomycin (VCM) as a class III drug (high solubility and low permeability) and griseofulvin (GF) as a class II drug (low solubility and high permeability), were employed to evaluate the potential of a polyglycolised glyceride carrier, namely Gelucire 44/14, to enhance their oral bioavailability. 2007-03 Thesis http://eprints.usm.my/9691/ http://eprints.usm.my/9691/1/INVESTIGATION_OF_THE_POTENTIAL_OF_GELUCIRE_44_14_FOR_ENHANCING_ORAL_BIOAVAILABILITY_USING_TWO_MODEL_DRUGS.pdf application/pdf en public masters Universiti Sains Malaysia Pusat Pengajian Sains Farmasi
institution Universiti Sains Malaysia
collection USM Institutional Repository
language English
topic RS1-441 Pharmacy and materia medica
spellingShingle RS1-441 Pharmacy and materia medica
Magosso, Enrico
Investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [RS199.5. M211 2007 f rb].
description Dua drug model yang termasuk dalam dua kumpulan Biopharmaceutics Classification System (BCS) yang berbeza, iaitu vancomycin (VCM), satu sebatian kelas III (keterlarutan tinggi dan ketelapan rendah), dan griseofulvin, satu drug kelas II (keterlarutan rendah and ketelapan tinggi) telah digunakan untuk menilai potensi satu pembawa gliserida berpoliglikol, iaitu Gelucire 44/14, untuk meningkatkan biokeperolehan oral. Two model drugs belonging to different groups of the Biopharmaceutics Classification System (BCS), which are vancomycin (VCM) as a class III drug (high solubility and low permeability) and griseofulvin (GF) as a class II drug (low solubility and high permeability), were employed to evaluate the potential of a polyglycolised glyceride carrier, namely Gelucire 44/14, to enhance their oral bioavailability.
format Thesis
qualification_level Master's degree
author Magosso, Enrico
author_facet Magosso, Enrico
author_sort Magosso, Enrico
title Investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [RS199.5. M211 2007 f rb].
title_short Investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [RS199.5. M211 2007 f rb].
title_full Investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [RS199.5. M211 2007 f rb].
title_fullStr Investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [RS199.5. M211 2007 f rb].
title_full_unstemmed Investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [RS199.5. M211 2007 f rb].
title_sort investigation of the potential of gelucire 44/14 for enhancing oral bioavailability using two model drugs [rs199.5. m211 2007 f rb].
granting_institution Universiti Sains Malaysia
granting_department Pusat Pengajian Sains Farmasi
publishDate 2007
url http://eprints.usm.my/9691/1/INVESTIGATION_OF_THE_POTENTIAL_OF_GELUCIRE_44_14_FOR_ENHANCING_ORAL_BIOAVAILABILITY_USING_TWO_MODEL_DRUGS.pdf
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