Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study

Blood velocity is expected to be a parameter for detecting blood abnormality, for example the existence of thrombus. Proper blood flow in veins are important to ensure the effective return of deoxygenated blood to the heart. It is challenging to determine the vessel condition, due to the inability t...

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Main Author: Aziz, Nur Shazilah
Format: Thesis
Language:English
English
English
Published: 2018
Subjects:
Online Access:http://eprints.uthm.edu.my/240/1/24p%20NUR%20SHAZILAH%20BT%20AZIZ.pdf
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spelling my-uthm-ep.2402021-07-13T03:23:27Z Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study 2018-05 Aziz, Nur Shazilah TK8300-8360 Photoelectronic devices (General) Blood velocity is expected to be a parameter for detecting blood abnormality, for example the existence of thrombus. Proper blood flow in veins are important to ensure the effective return of deoxygenated blood to the heart. It is challenging to determine the vessel condition, due to the inability to visualize the thrombus presence in the vessel. This is due to the noise that are present in the image obtained from Ultrasound scanning. Since it is difficult to recognize the vessel condition at the earliest stage of Deep Vein Thrombosis (DVT), this study aims to assess the velocity and vorticity at the valve region using the Computational Fluid Dynamics (CFD) method. The velocity ofblood and the size of valve orifice are considered important parameters in designing the vein. Following Virchow's triad theory, the stenosis and irregularities of velocity in the blood vessel are known as the risk factors for thrombus formation. This study also includes the effect of different sizes of valve orifice with the existence of 1 mm and 3 mm thrombus, as both represent the DVT condition. From the simulation, the velocity contour plot of the blood flow can be visualised clearly. The blood distribution was presented using velocity profile while the fluid particles movement was shown by velocity vector. Vorticity contour meanwhile provides information on the tendency of particles to move in circular motion. Based on the simulation, the low blood velocity clearly shows the low velocity region which resides at the cusps area and at the beginning of the valve leaflets. Therefore, the present study has successfully shown that the CFD method is able to determine and evaluate the probable location of thrombus development in the blood vessel. 2018-05 Thesis http://eprints.uthm.edu.my/240/ http://eprints.uthm.edu.my/240/1/24p%20NUR%20SHAZILAH%20BT%20AZIZ.pdf text en public http://eprints.uthm.edu.my/240/2/NUR%20SHAZILAH%20BT%20AZIZ%20COPYRIGHT%20DECLARATION.pdf text en staffonly http://eprints.uthm.edu.my/240/3/NUR%20SHAZILAH%20BT%20AZIZ%20WATERMARK.pdf text en validuser mphil masters Universiti Tun Hussein Onn Malaysia Faculty of Electrical and Electronic Engineering
institution Universiti Tun Hussein Onn Malaysia
collection UTHM Institutional Repository
language English
English
English
topic TK8300-8360 Photoelectronic devices (General)
spellingShingle TK8300-8360 Photoelectronic devices (General)
Aziz, Nur Shazilah
Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
description Blood velocity is expected to be a parameter for detecting blood abnormality, for example the existence of thrombus. Proper blood flow in veins are important to ensure the effective return of deoxygenated blood to the heart. It is challenging to determine the vessel condition, due to the inability to visualize the thrombus presence in the vessel. This is due to the noise that are present in the image obtained from Ultrasound scanning. Since it is difficult to recognize the vessel condition at the earliest stage of Deep Vein Thrombosis (DVT), this study aims to assess the velocity and vorticity at the valve region using the Computational Fluid Dynamics (CFD) method. The velocity ofblood and the size of valve orifice are considered important parameters in designing the vein. Following Virchow's triad theory, the stenosis and irregularities of velocity in the blood vessel are known as the risk factors for thrombus formation. This study also includes the effect of different sizes of valve orifice with the existence of 1 mm and 3 mm thrombus, as both represent the DVT condition. From the simulation, the velocity contour plot of the blood flow can be visualised clearly. The blood distribution was presented using velocity profile while the fluid particles movement was shown by velocity vector. Vorticity contour meanwhile provides information on the tendency of particles to move in circular motion. Based on the simulation, the low blood velocity clearly shows the low velocity region which resides at the cusps area and at the beginning of the valve leaflets. Therefore, the present study has successfully shown that the CFD method is able to determine and evaluate the probable location of thrombus development in the blood vessel.
format Thesis
qualification_name Master of Philosophy (M.Phil.)
qualification_level Master's degree
author Aziz, Nur Shazilah
author_facet Aziz, Nur Shazilah
author_sort Aziz, Nur Shazilah
title Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_short Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_full Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_fullStr Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_full_unstemmed Visualisation on blood flow mechanism of vein in deep vein thrombosis (DVT) study
title_sort visualisation on blood flow mechanism of vein in deep vein thrombosis (dvt) study
granting_institution Universiti Tun Hussein Onn Malaysia
granting_department Faculty of Electrical and Electronic Engineering
publishDate 2018
url http://eprints.uthm.edu.my/240/1/24p%20NUR%20SHAZILAH%20BT%20AZIZ.pdf
http://eprints.uthm.edu.my/240/2/NUR%20SHAZILAH%20BT%20AZIZ%20COPYRIGHT%20DECLARATION.pdf
http://eprints.uthm.edu.my/240/3/NUR%20SHAZILAH%20BT%20AZIZ%20WATERMARK.pdf
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