Preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification

The purpose of this study is to determine the potential of cellulose acetate membrane for preparation of formulated water-in-oil-in-water (W/O/W) emulsions by repeated premix membrane emulsification. The effects of selective membrane emulsification process parameters (concentration of the emulsifier...

Full description

Saved in:

Bibliographic Details
Main Author:	Chang, Hui Quin
Format:	Thesis
Language:	English
Published:	2012
Subjects:	TP Chemical technology
Online Access:	http://eprints.utm.my/id/eprint/35883/1/ChangHuiQuinMFKK2012.pdf
Tags:	Add Tag No Tags, Be the first to tag this record!

id	my-utm-ep.35883
record_format	uketd_dc
spelling	my-utm-ep.358832017-09-21T04:09:10Z Preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification 2012-11 Chang, Hui Quin TP Chemical technology The purpose of this study is to determine the potential of cellulose acetate membrane for preparation of formulated water-in-oil-in-water (W/O/W) emulsions by repeated premix membrane emulsification. The effects of selective membrane emulsification process parameters (concentration of the emulsifiers, number of passes of the emulsions through the membrane, and storage temperature) on the properties and stability of W/O/W emulsions were also investigated. The preparation of multiple W/O/W emulsions by repeated premix membrane emulsification (ME) using cellulose acetate membrane (0.8 µm mean pore size) has proposed in this study to reduce low stability problem of the emulsions. A coarse emulsion was passed through the same membrane five times at a constant pressure of 0.3 MPa to minimize the droplets size and to increase the uniformity of droplets size. About 7 wt. % polyglycerol polyricinoleate (PGPR) and 0.5-10 wt. % Tween 80 (Polyoxyethylene (20) sorbitan monooleate) were used as lipophilic and hydrophilic emulsifiers, respectively. In addition, 1,3,6,8-pyrenetetrasulfonic acid tetrasodium salt (PTSA) was used as a hydrophilic model ingredient for the encapsulation of bioactive substances. By using 7 wt. % PGPR concentration and 0.5 wt. % Tween 80 concentrations, the most uniform particles with minimum mean size of oil drops (9.926 µm) were obtained after four passes through the membrane. The encapsulation efficiency greater than 70 % was achieved after emulsions storage at 4°C for seven days with amount of serum about 41.02%. It can be concluded that cellulose acetate membrane does not possess very high potential for preparing a stable W/O/W emulsion by repeated premix membrane emulsification. However, this membrane is still acceptable for preparing W/O/W emulsions with the optimum conditions (0.8 µm mean pore size and applying pressure of 0.3 MPa) obtained throughout this study since cellulose acetate membrane is low cost and relatively easy to handle. 2012-11 Thesis http://eprints.utm.my/id/eprint/35883/ http://eprints.utm.my/id/eprint/35883/1/ChangHuiQuinMFKK2012.pdf application/pdf en public masters Universiti Teknologi Malaysia, Faculty of Chemical Engineering Faculty of Chemical Engineering
institution	Universiti Teknologi Malaysia
collection	UTM Institutional Repository
language	English
topic	TP Chemical technology
spellingShingle	TP Chemical technology Chang, Hui Quin Preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification
description	The purpose of this study is to determine the potential of cellulose acetate membrane for preparation of formulated water-in-oil-in-water (W/O/W) emulsions by repeated premix membrane emulsification. The effects of selective membrane emulsification process parameters (concentration of the emulsifiers, number of passes of the emulsions through the membrane, and storage temperature) on the properties and stability of W/O/W emulsions were also investigated. The preparation of multiple W/O/W emulsions by repeated premix membrane emulsification (ME) using cellulose acetate membrane (0.8 µm mean pore size) has proposed in this study to reduce low stability problem of the emulsions. A coarse emulsion was passed through the same membrane five times at a constant pressure of 0.3 MPa to minimize the droplets size and to increase the uniformity of droplets size. About 7 wt. % polyglycerol polyricinoleate (PGPR) and 0.5-10 wt. % Tween 80 (Polyoxyethylene (20) sorbitan monooleate) were used as lipophilic and hydrophilic emulsifiers, respectively. In addition, 1,3,6,8-pyrenetetrasulfonic acid tetrasodium salt (PTSA) was used as a hydrophilic model ingredient for the encapsulation of bioactive substances. By using 7 wt. % PGPR concentration and 0.5 wt. % Tween 80 concentrations, the most uniform particles with minimum mean size of oil drops (9.926 µm) were obtained after four passes through the membrane. The encapsulation efficiency greater than 70 % was achieved after emulsions storage at 4°C for seven days with amount of serum about 41.02%. It can be concluded that cellulose acetate membrane does not possess very high potential for preparing a stable W/O/W emulsion by repeated premix membrane emulsification. However, this membrane is still acceptable for preparing W/O/W emulsions with the optimum conditions (0.8 µm mean pore size and applying pressure of 0.3 MPa) obtained throughout this study since cellulose acetate membrane is low cost and relatively easy to handle.
format	Thesis
qualification_level	Master's degree
author	Chang, Hui Quin
author_facet	Chang, Hui Quin
author_sort	Chang, Hui Quin
title	Preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification
title_short	Preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification
title_full	Preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification
title_fullStr	Preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification
title_full_unstemmed	Preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification
title_sort	preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification
granting_institution	Universiti Teknologi Malaysia, Faculty of Chemical Engineering
granting_department	Faculty of Chemical Engineering
publishDate	2012
url	http://eprints.utm.my/id/eprint/35883/1/ChangHuiQuinMFKK2012.pdf
_version_	1747816379095973888

Preparation of water-in-oil-in-water emulsions by repeated premix cellulose acetate membrane emulsification

Similar Items