Finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment

Hyperthermia treatment has been used to treat brain tumor diseases where conventional surgical removal is invasive and poses threat to a patient. The treatment technique is to apply microwave energy which transforms into heat on the target tumour without overheating surrounding healthy tissue. The i...

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Main Author:	Lee, Chia Wui
Format:	Thesis
Language:	English
Published:	2015
Subjects:	TK Electrical engineering Electronics Nuclear engineering
Online Access:	http://eprints.utm.my/id/eprint/54080/1/LeeChiaWuiMFKE2015.pdf
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spelling	my-utm-ep.540802020-10-19T08:59:49Z Finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment 2015-11 Lee, Chia Wui TK Electrical engineering. Electronics Nuclear engineering Hyperthermia treatment has been used to treat brain tumor diseases where conventional surgical removal is invasive and poses threat to a patient. The treatment technique is to apply microwave energy which transforms into heat on the target tumour without overheating surrounding healthy tissue. The insulated monopole has proven to be suitable as an applicator in hyperthermia treatment whereby its thin slot form and small cross section area allows it to reach deep seated brain tumour. Nowadays, simulation is used to evaluate insulated monopole design. However, existing commercial simulators are difficult to learn and operate. In this study, a simple and user friendly finite-difference-time-domain (FDTD) based simulator written in MATLAB codes is developed for hyperthermia brain tumour treatment. Using the developed simulator, electric field, specific-absorption-rate (SAR) distribution and reflection coefficient of two designed insulated monopoles have been studied. The first designed insulated monopole is a simple insulated monopole with thin air gap. The second design is a multi-layer insulated monopole used to treat large deep-seated brain tumour. The resulting electric field and SAR distribution were compared and validated against analytical solutions and commercial simulator’s results, respectively. The simulator’s result was found to be more accurate with less reflection at the wave scatter boundary when complex frequency shifted perfectly matched layer (CFS-PML) absorbing boundary condition was used. And the optimal parameters of the absorbing boundary condition CFSPML in reducing computation cost were identified to be 10 layers with the degree of polynomial, m = 4. 2015-11 Thesis http://eprints.utm.my/id/eprint/54080/ http://eprints.utm.my/id/eprint/54080/1/LeeChiaWuiMFKE2015.pdf application/pdf en public http://dms.library.utm.my:8080/vital/access/manager/Repository/vital:86672 masters Universiti Teknologi Malaysia, Faculty of Electrical Engineering Faculty of Electrical Engineering
institution	Universiti Teknologi Malaysia
collection	UTM Institutional Repository
language	English
topic	TK Electrical engineering Electronics Nuclear engineering
spellingShingle	TK Electrical engineering Electronics Nuclear engineering Lee, Chia Wui Finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment
description	Hyperthermia treatment has been used to treat brain tumor diseases where conventional surgical removal is invasive and poses threat to a patient. The treatment technique is to apply microwave energy which transforms into heat on the target tumour without overheating surrounding healthy tissue. The insulated monopole has proven to be suitable as an applicator in hyperthermia treatment whereby its thin slot form and small cross section area allows it to reach deep seated brain tumour. Nowadays, simulation is used to evaluate insulated monopole design. However, existing commercial simulators are difficult to learn and operate. In this study, a simple and user friendly finite-difference-time-domain (FDTD) based simulator written in MATLAB codes is developed for hyperthermia brain tumour treatment. Using the developed simulator, electric field, specific-absorption-rate (SAR) distribution and reflection coefficient of two designed insulated monopoles have been studied. The first designed insulated monopole is a simple insulated monopole with thin air gap. The second design is a multi-layer insulated monopole used to treat large deep-seated brain tumour. The resulting electric field and SAR distribution were compared and validated against analytical solutions and commercial simulator’s results, respectively. The simulator’s result was found to be more accurate with less reflection at the wave scatter boundary when complex frequency shifted perfectly matched layer (CFS-PML) absorbing boundary condition was used. And the optimal parameters of the absorbing boundary condition CFSPML in reducing computation cost were identified to be 10 layers with the degree of polynomial, m = 4.
format	Thesis
qualification_level	Master's degree
author	Lee, Chia Wui
author_facet	Lee, Chia Wui
author_sort	Lee, Chia Wui
title	Finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment
title_short	Finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment
title_full	Finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment
title_fullStr	Finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment
title_full_unstemmed	Finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment
title_sort	finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment
granting_institution	Universiti Teknologi Malaysia, Faculty of Electrical Engineering
granting_department	Faculty of Electrical Engineering
publishDate	2015
url	http://eprints.utm.my/id/eprint/54080/1/LeeChiaWuiMFKE2015.pdf
_version_	1747817680666099712

Finite-difference-time-domain simulation of insulated monopole in brain tumor hyperthermia treatment

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