Phytochemistry and antioxidant activity of selected species from lauraceae family
<p>The purposes of the study were to analyse the essential oils composition,</p><p>phytochemicals, and antioxidant activity of selected species of the genus Litsea (L.</p><p>costalis, L. machilifolia and L. globularia), Beilschmie...
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| Format: | thesis |
| Language: | eng |
| Published: |
2021
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| Subjects: | |
| Online Access: | https://ir.upsi.edu.my/detailsg.php?det=7114 |
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| Summary: | <p>The purposes of the study were to analyse the essential oils composition,</p><p>phytochemicals, and antioxidant activity of selected species of the genus Litsea (L.</p><p>costalis, L. machilifolia and L. globularia), Beilschmiedia (B. kunstleri, B. insignis</p><p>and B. pahangensis) and Cryptocarya (C. impressa, C. infectoria and C. rugulosa)</p><p>from Lauraceae family. The essential oils were obtained via hydrodistillation</p><p>technique and their chemical compositions were determined by gas chromatography</p><p>(GC-FID) and gas chromatography-mass spectrometry (GC-MS). The phytochemicals</p><p>were obtained using chromatography techniques and their structures were confirmed</p><p>by spectroscopic analysis and comparison with literature. The antioxidant activity of</p><p>the essential oils and extracts was determined using DPPH free radical scavenging</p><p>assay. The study showed that the major components of L. costalis, L. machilifolia and</p><p>L. globularia essential oils were -caryophyllene (12.6%), -sesquiphellandrene</p><p>(29.5%) and -caryophyllene (25.2%), respectively. Besides, -longipinene (11.0%),</p><p>(E)-nerolidol (32.4%) and -cadinene were the major components from the essential</p><p>oils of B. kunstleri, B. insignis and B. pahangensis, respectively. As for C. impressa,</p><p>C. infectoria and C. rugulosa, the essential oils consisted of -cadinol (40.7%), -</p><p>caryophyllene (25.4%) and bicyclogermacrene (15.6%), respectively. The</p><p>dichloromethane and methanol extracts of B. insignis yielded seven phytochemicals</p><p>identified as vanillic acid, vanillin, benzyl benzoate, benzoic acid, betulin, -sitosterol</p><p>and -sitostenone. All essential oils displayed weak activity in DPPH radical</p><p>scavenging assay, while the L. costalis methanolic extract showed the strongest</p><p>activity (IC50 21.9 ppm) comparable to ascorbic acid (IC50 2.9 ppm). In conclusion,</p><p>the major composition of essential oils was sesquiterpene hydrocarbons, meanwhile</p><p>carboxylic acids and terpenes were successfully isolated from B. insignis extracts. The</p><p>implication of the study showed the essential oils and extracts of the genus Litsea,</p><p>Beilschmiedia and Cryptocarya have potential in pharmaceutical applications.</p> |
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