Preparation, characterisation and effectiveness of nanocomposites based on Go-Fe3O4 as nanocarriers for insecticide compounds

<p>This research aimed to prepare, characterise and study the effectiveness of two</p><p>magnetic graphene oxide-based nanocomposites, namely gellan gum-graphene</p><p>oxide (GG-GO-Fe3O4) and pectin-graphene oxide (PEC-GO-Fe3O4) a...

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Main Author: Wong, Susana Siew Tin
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Language:eng
Published: 2022
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institution Universiti Pendidikan Sultan Idris
collection UPSI Digital Repository
language eng
topic QD Chemistry
spellingShingle QD Chemistry
Wong, Susana Siew Tin
Preparation, characterisation and effectiveness of nanocomposites based on Go-Fe3O4 as nanocarriers for insecticide compounds
description <p>This research aimed to prepare, characterise and study the effectiveness of two</p><p>magnetic graphene oxide-based nanocomposites, namely gellan gum-graphene</p><p>oxide (GG-GO-Fe3O4) and pectin-graphene oxide (PEC-GO-Fe3O4) as</p><p>nanocarriers for permethrin and cinnamaldehyde insecticide compounds. This</p><p>research is divided into three parts, namely preparation, characterisation and</p><p>effectiveness studies. Nanocomposites with amorphous structure were</p><p>successfully produced based on the existence of conjugation mechanism between</p><p>GG and PEC with iron oxide at wavenumber peak 650 cm-1. Results from</p><p>thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC)</p><p>have shown that the nanocomposites loaded with insecticides are thermally stable.</p><p>Performance study of nanocomposites loaded with insecticides towards Aedes</p><p>aegypti larvae was analysed through Abbotts and Probits formula via in vitro at</p><p>different pH using ultraviolet-visible (UV-Vis) spectrometer. The encapsulation</p><p>of insecticide to nanocarriers was successfully carried out based on the change in</p><p>intensity and wavenumber of absorption bands from Fourier Transform Infrared</p><p>Spectrometer (FTIR) analysis and size increment of nanocarriers in the range of</p><p>18.2 to 70.1%. The formulated nanocarriers have successfully prolonged the</p><p>release duration of permethrin and cinnamaldehyde by 15 and 24 hours,</p><p>respectively. The release profiles of insecticide compounds were best fitted by</p><p>Korsemeyer-Peppas kinetic model. Formulation of GG-GO-Fe3O4 nanocarrier</p><p>loaded with cinnamaldehyde was found as the most effective formulation to</p><p>control A. aegypti larvae. In conclusion, both nanocarriers studied have shown</p><p>outstanding performance in loading and releasing permethrin and cinnamaldehyde</p><p>in larvicide formulations. In implication, the application of both environmental</p><p>friendly nanocarriers in larvicide formulations could reduce mosquito borne</p><p>diseases and sustain the environment.</p>
format thesis
qualification_name
qualification_level Master's degree
author Wong, Susana Siew Tin
author_facet Wong, Susana Siew Tin
author_sort Wong, Susana Siew Tin
title Preparation, characterisation and effectiveness of nanocomposites based on Go-Fe3O4 as nanocarriers for insecticide compounds
title_short Preparation, characterisation and effectiveness of nanocomposites based on Go-Fe3O4 as nanocarriers for insecticide compounds
title_full Preparation, characterisation and effectiveness of nanocomposites based on Go-Fe3O4 as nanocarriers for insecticide compounds
title_fullStr Preparation, characterisation and effectiveness of nanocomposites based on Go-Fe3O4 as nanocarriers for insecticide compounds
title_full_unstemmed Preparation, characterisation and effectiveness of nanocomposites based on Go-Fe3O4 as nanocarriers for insecticide compounds
title_sort preparation, characterisation and effectiveness of nanocomposites based on go-fe3o4 as nanocarriers for insecticide compounds
granting_institution Universiti Pendidikan Sultan Idris
granting_department Fakulti Sains dan Matematik
publishDate 2022
url https://ir.upsi.edu.my/detailsg.php?det=8818
_version_ 1776104568380194816
spelling oai:ir.upsi.edu.my:88182023-03-29 Preparation, characterisation and effectiveness of nanocomposites based on Go-Fe3O4 as nanocarriers for insecticide compounds 2022 Wong, Susana Siew Tin QD Chemistry <p>This research aimed to prepare, characterise and study the effectiveness of two</p><p>magnetic graphene oxide-based nanocomposites, namely gellan gum-graphene</p><p>oxide (GG-GO-Fe3O4) and pectin-graphene oxide (PEC-GO-Fe3O4) as</p><p>nanocarriers for permethrin and cinnamaldehyde insecticide compounds. This</p><p>research is divided into three parts, namely preparation, characterisation and</p><p>effectiveness studies. Nanocomposites with amorphous structure were</p><p>successfully produced based on the existence of conjugation mechanism between</p><p>GG and PEC with iron oxide at wavenumber peak 650 cm-1. Results from</p><p>thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC)</p><p>have shown that the nanocomposites loaded with insecticides are thermally stable.</p><p>Performance study of nanocomposites loaded with insecticides towards Aedes</p><p>aegypti larvae was analysed through Abbotts and Probits formula via in vitro at</p><p>different pH using ultraviolet-visible (UV-Vis) spectrometer. The encapsulation</p><p>of insecticide to nanocarriers was successfully carried out based on the change in</p><p>intensity and wavenumber of absorption bands from Fourier Transform Infrared</p><p>Spectrometer (FTIR) analysis and size increment of nanocarriers in the range of</p><p>18.2 to 70.1%. The formulated nanocarriers have successfully prolonged the</p><p>release duration of permethrin and cinnamaldehyde by 15 and 24 hours,</p><p>respectively. The release profiles of insecticide compounds were best fitted by</p><p>Korsemeyer-Peppas kinetic model. Formulation of GG-GO-Fe3O4 nanocarrier</p><p>loaded with cinnamaldehyde was found as the most effective formulation to</p><p>control A. aegypti larvae. In conclusion, both nanocarriers studied have shown</p><p>outstanding performance in loading and releasing permethrin and cinnamaldehyde</p><p>in larvicide formulations. In implication, the application of both environmental</p><p>friendly nanocarriers in larvicide formulations could reduce mosquito borne</p><p>diseases and sustain the environment.</p> 2022 thesis https://ir.upsi.edu.my/detailsg.php?det=8818 https://ir.upsi.edu.my/detailsg.php?det=8818 text eng closedAccess Masters Universiti Pendidikan Sultan Idris Fakulti Sains dan Matematik <p>AbellaMedrano, C. A., Roiz, D., Islas, C. G. R., SalazarJurez, C. L., & OjedaFlores,</p><p>R. (2020). Assemblage variation of mosquitoes (Diptera: Culicidae) in different</p><p>land use and activity periods within a lowland tropical forest matrix in</p><p>Campeche, Mexico. Journal of Vector Ecology, 45(2), 188-196.</p><p></p><p>Ahn, Y. J., Kim, N. J., Byun, S. G., Cho, J. E., & Chung, K. (2008). Larvicidal activity</p><p>of Kaempferia galanga rhizome phenylpropanoids towards three mosquito</p><p>species. Pest Management Science: formerly Pesticide Science, 64(8), 857-862.</p><p></p><p>Akhtar, K., Khan, S. A., Khan, S. B., & Asiri, A. M. (2018). Scanning electron</p><p>microscopy: Principle and applications in nanomaterials characterization.</p><p>In Handbook of materials characterization (pp. 113-145). Astemdam: Springer.</p><p></p><p>Aldersley, A., & Cator, L. J. (2019). Female resistance and harmonic convergence</p><p>influence male mating success in Aedes aegypti. Scientific Reports, 9(1), 1-12.</p><p>Ali, H. (2016). Reaction mechanism in organic chemistry. India: S. Chand and</p><p>Company Limited.</p><p></p><p>Anuar, A. A., & Yusof, N. (2016). Methods of imparting mosquito repellent agents and</p><p>the assessing mosquito repellency on textile. Fashion and Textiles, 3(1), 1-14.</p><p></p><p>Ashakirin, S. N., Tripathy, M., Patil, U. K., & Majeed, A. A. (2017). Chemistry and</p><p>bioactivity of cinnamaldehyde: a natural molecule of medicinal importance. Int.</p><p>Journal of Pharmaceutical Sciences and Research, 8(6), 2333-2340.</p><p></p><p>Ashburn, P. M., & Caraig, C. F. (1907). Experimental investigations regarding the</p><p>etiology of dengue fever. The Journal of Infectious Diseases, 440-475.</p><p></p><p>Aziz, M., Halim, F. S. A., & Jaafar, J. (2014). Preparation and characterization of</p><p>graphene membrane electrode assembly. Jurnal Teknologi, 69(9).</p><p></p><p>Balci, M. (2005). Basic 1H-and 13C-NMR spectroscopy. Asterdam: Elsevier.</p><p></p><p>Baldacchino, F., Caputo, B., Chandre, F., Drago, A., della Torre, A., Montarsi, F., &</p><p>Rizzoli, A. (2015). Control methods against invasive Aedes mosquitoes in</p><p>Europe: a review. Pest Management Science, 71(11), 1471-1485.</p><p></p><p>Bancroft, T. L. (1906). On the aetiology of dengue fever. Austral. Med. Gaz., 25, 17-</p><p>18.</p><p></p><p>Barrera-Mndez, F., Ibarra-Juarez, L. A., Hernndez-Cervantes, G., Cruz, S. X. R.,</p><p>Vzquez, M., Prez-Landa, I. D., Bonila-Landa, I & Olivares-Romero, J. L.</p><p>(2021). Nanoencapsulation of permethrin in polylactic acid to enhance</p><p>insecticide persistence for scolytinae pest control. Journal of Nano Research,</p><p>66, 143-152.</p><p></p><p>Bacsik, Z., Mink, J., & Keresztury, G. (2004). FTIR spectroscopy of the atmosphere. I.</p><p>Principles and methods. Applied Spectroscopy Reviews, 39(3), 295-363.</p><p></p><p>Balachandramohan, J., Anandan, S., & Sivasankar, T. (2018). A simple approach for</p><p>the sonochemical synthesis of Fe3O4-guargum nanocomposite and its catalytic</p><p>reduction of p-nitroaniline. Ultrasonics Sonochemistry, 40, 1-10.</p><p></p><p>Becker, N. (2008). Influence of climate change on mosquito development and</p><p>mosquito-borne diseases in Europe. Parasitology Research, 103(1), 19-28.</p><p></p><p>Beh, C. C., Mammucari, R., & Foster, N. (2016). Process intensification and</p><p>sustainability in chemical engineering. Chemeca 2016: Chemical Engineering-</p><p>Regeneration, Recovery and Reinvention, 453.</p><p></p><p>Benedict, M. Q., Knols, B. G., Bossin, H. C., Howell, P. I., Mialhe, E., Caceres, C., &</p><p>Robinson, A. S. (2009). Colonisation and mass rearing: learning from</p><p>others. Malaria Journal, 8(2), 1-11.</p><p></p><p>Bhatia, S. (2016). Nanoparticles types, classification, characterization, fabrication</p><p>methods and drug delivery applications. In Natural Polymer Drug Delivery</p><p>Systems(pp. 33-93). Switzerland: Springer.</p><p></p><p>Bhosale, R. R., Gangadharappa, H. V., Osmani, R. A. M., & Gowda, D. V. (2020).</p><p>Design and development of polymethylmethacrylate-grafted gellan gum</p><p>(PMMA-g-GG)-based pH-sensitive novel drug delivery system for antidiabetic</p><p>therapy. Drug Delivery and Translational Research, 10, 1002-1018.</p><p></p><p>Bisht, S., Feldmann, G., Soni, S., Ravi, R., Karikar, C., Maitra, A., & Maitra, A. (2007).</p><p>Polymeric nanoparticle-encapsulated curcumin (" nanocurcumin"): a novel</p><p>strategy for human cancer therapy. Journal of Nanobiotechnology, 5(1), 1-18.</p><p></p><p>Bowen, M. F. (1996). Sensory aspects of host location in mosquitoes. In Bock, G.P. &</p><p>Cardew, G. (Eds), Olfaction in MosquitoHost Interactions (pp. 197-211).</p><p>West Sussex, England: John Wiley & Sons Ltd.</p><p></p><p>Boykin, A. W. (2020). The triple quandary and the schooling of Afro-American</p><p>children. In The school achievement of minority children (pp. 57-92).</p><p>Oxfordshire, UK: Routledge.</p><p></p><p>Bradberry, S. M., Cage, S. A., Proudfoot, A. T., & Vale, J. A. (2005). Poisoning due to</p><p>pyrethroids. Toxicological Reviews, 24(2), 93-106.</p><p></p><p>Branco, A. C. C. C., Yoshikawa, F. S. Y., Pietrobon, A. J., & Sato, M. N. (2018). Role</p><p>of histamine in modulating the immune response and inflammation. Mediators</p><p>of Inflammation, 2018.</p><p></p><p>Bravo, L., Roque, V. G., Brett, J., Dizon, R., & L'Azou, M. (2014). Epidemiology of</p><p>dengue disease in the Philippines (20002011): a systematic literature</p><p>review. PLoS Neglected Tropical Diseases, 8(11), e3027.</p><p></p><p>Brown, M.E. (Ed.) (2004). Introduction to thermal analysis: Technique and</p><p>applications. London: Kluwer Academic Publisher.</p><p></p><p>Bykkam, S., Rao, K., Chakra, C., & Thunugunta, T. (2013). Synthesis and</p><p>characterization of graphene oxide and its antimicrobial activity against</p><p>klebseilla and staphylococus. International Journal of Advanced Biotechnology</p><p>and Research, 4(1), 142-146.</p><p></p><p>Byttebier, B., De Majo, M. S., & Fischer, S. (2014). Hatching response of Aedes</p><p>aegypti (Diptera: Culicidae) eggs at low temperatures: effects of hatching media</p><p>and storage conditions.Journal of Medical Entomology,51(1), 97-103.</p><p></p><p>Campos, D. A., Madureira, A. R., Sarmento, B., Gomes, A. M., & Pintado, M. M.</p><p>(2015). Stability of bioactive solid lipid nanoparticles loaded with herbal</p><p>extracts when exposed to simulated gastrointestinal tract conditions. Food</p><p>Research International, 78, 131-140.</p><p></p><p>Carpenter, S. J. & LaCasse, W. (1974). Mosquitoes of north america (north of mexico).</p><p>Berkeley, California: University of California Press.</p><p></p><p>Carrington, L. B., & Simmons, C. P. (2014). Human to mosquito transmission of</p><p>dengue viruses. Frontiers in Immunology, 5, 290.</p><p></p><p>Cator, L. J., Arthur, B. J., Harrington, L. C., & Hoy, R. R. (2009). Harmonic</p><p>convergence in the love songs of the dengue vector</p><p>mosquito. Science, 323(5917), 1077-1079.</p><p></p><p>Carvalho, F.D. & Moreira, L.A. (2017). Why is Aedes aegypti Linnaeus so successful</p><p>as a species? Neotropical Entomology, 46, 233-255.</p><p></p><p>Cazes, J. (Ed.). (2004). Ewing's Analytical instrumentation handbook (3rd ed.). Florida,</p><p>USA: CRC Press.</p><p></p><p>Centre for Diseases Control and Prevention (CDC). (2021). Dengue Vaccine. Retrieved</p><p>from https://www.cdc.gov/dengue/prevention/dengue-vaccine.html</p><p></p><p>Chakraborty, M., & Hashmi, M. S. J. (2018). Wonder material graphene: Properties,</p><p>synthesis and practical applications. Advances in Materials and Processing</p><p>Technologies, 4(4), 573-602.</p><p></p><p>Chen, C. D., Nazni, W. A., Lee, H. L., & Sofian-Azirun, M. (2005). Weekly variation</p><p>on susceptibility status of Aedes mosquitoes against temephos in Selangor,</p><p>Malaysia. Tropical Biomedicine, 22(2), 195-206.</p><p></p><p>Chen, J., Yao, B., Li, C., & Shi, G. (2013). An improved Hummers method for ecofriendly</p><p>synthesis of graphene oxide. Carbon, 64, 225-229.</p><p></p><p>Cheng, S. S., Huang, C. G., Chen, Y. J., Yu, J. J., Chen, W. J., & Chang, S. T. (2009).</p><p>Chemical compositions and larvicidal activities of leaf essential oils from two</p><p>eucalyptus species. Bioresource Technology, 100(1), 452-456.</p><p></p><p>Cheong, Y. L., Burkart, K., Leito, P. J., & Lakes, T. (2013). Assessing weather effects</p><p>on dengue disease in Malaysia. International Journal of Environmental</p><p>Research And Public Health, 10(12), 6319-6334.</p><p></p><p>Chia, P. Y., Thein, T. L., Ong, S. W. X., Lye, D. C., & Leo, Y. S. (2020). Severe dengue</p><p>and liver involvement: an overview and review of the literature. Expert Review</p><p>of Anti-Infective Therapy, 18(3), 181-189.</p><p></p><p>Chime, S. A., Ugwuoke, E. C., Onyishi, I. V., Brown, S. A., & Onunkwo, G. C. (2013).</p><p>Formulation and evaluation of Alstonia boonei stem bark powder tablets. Indian</p><p>Journal Of Pharmaceutical Sciences, 75(2), 226.</p><p></p><p>Cho, S.S. & Dreher, M.L. (Eds). (2001). Handbook of dietary fibre. New York: CRC</p><p>Press.</p><p></p><p>Clements, A. N. (2013). The Physiology of Mosquitoes: International Series of</p><p>Monographs on Pure and Applied Biology: Zoology, Vol. 17 (Vol. 17). Elsevier.</p><p></p><p>Cox, J., Mota, J., Sukupolvi-Petty, S., Diamond, M. S., & Rico-Hesse, R. (2012).</p><p>Mosquito bite delivery of dengue virus enhances immunogenicity and</p><p>pathogenesis in humanized mice. Journal of Virology, 86(14), 7637-7649.</p><p></p><p>Cruz-Oliveira, C., Freire, J. M., Conceio, T. M., Higa, L. M., Castanho, M. A., & Da</p><p>Poian, A. T. (2015). Receptors and routes of dengue virus entry into the host</p><p>cells. FEMS Microbiology Reviews, 39(2), 155-170.</p><p></p><p>Custdio, K. M., Oliveira, J. G. D., Moterle, D., Zepon, K. M., Prophiro, J. S., & Kanis,</p><p>L. A. (2016). A biodegradable device for the controlled release of Piper nigrum</p><p>(Piperaceae) standardized extract to control Aedes aegypti (Diptera, Culicidae)</p><p>larvae. Revista da Sociedade Brasileira de Medicina Tropical, 49, 687-692.</p><p></p><p>da Silva, J. K. R., Andrade, E. H. A., Kato, M. J., Carreira, L. M. M., Guimaraes, E. F.,</p><p>& Maia, J. G. S. (2011). Antioxidant capacity and larvicidal and antifungal</p><p>activities of essential oils and extracts from Piper krukoffii. Natural Product</p><p>Communications, 6(9), 1934578X1100600936.</p><p></p><p>Department of Statistics Malaysia, DOSM (2017). Population: Ulu Langat (Hulu</p><p>Langat). Retrieved from https://www.citypopulation.de/en/malaysia/admin/</p><p>selangor/1008__ulu_langat/</p><p></p><p>Department of Statistics Malaysia, DOSM (2021). Population & demographic.</p><p>Retrieved from https://www.dosm.gov.my/v1/index.php?r=column/ctwoBy</p><p>Cat&parent_id=115&menu_id=L0pheU43NWJwRWVSZklWdzQ4TlhUUT0</p><p>9</p><p></p><p>de Almeida Costa, E.A.P, de Mendona Santos, E.M., Correia, J.C. & de Albuquerque,</p><p>C.M.R. (2010). Impact of small variations in temperature and humidity on the</p><p>reproductive activity and survival of Aedes aegypti (Diptera, Culicidae).</p><p>Revista Brasileira de Entomologia, 54(3), 488-493.</p><p></p><p>Dick, O. B., San Martn, J. L., Montoya, R. H., del Diego, J., Zambrano, B., & Dayan,</p><p>G. H. (2012). The history of dengue o1utbreaks in the Americas. The American</p><p>Journal of Tropical Medicine and Hygiene, 87(4), 584-593.</p><p></p><p>Din, F., Aman, W., Ullah, I., Qureshi, O. S., Mustapha, O., Shafique, S., & Zeb, A.</p><p>(2017). Effective use of nanocarriers as drug delivery systems for the treatment</p><p>of selected tumors. International Journal Of Nanomedicine, 12, 7291.</p><p></p><p>Ding, C., & Li, Z. (2017). A review of drug release mechanisms from nanocarrier</p><p>systems. Materials Science and Engineering: C, 76, 1440-1453.</p><p></p><p>Dreyer, D. R., Park, S., Bielawski, C. W., & Ruoff, R. S. (2010). The chemistry of</p><p>graphene oxide. Chemical Society Reviews, 39(1), 228-240.</p><p></p><p>Edman, J. D., & Spielman, A. (2020). Blood-feeding by vectors: physiology, ecology,</p><p>behavior, and vertebrate defense. In Monath, T.P. (Ed.) The Arboviruses:</p><p>Epidemiology and Ecology (pp. 153-190). Oxfordshire, UK: Taylor & Francis.</p><p></p><p>Edwards, W.P. (2019). The science of sugar confectionary (2nd ed.). United Kingdom:</p><p>Royal Society of Chemistry.</p><p></p><p>Erdman,N., Bell, D.C. & Reichelt, R. (2019). Scanning electron microscopy. In</p><p>Hawkes, P.W. & Spence, J.C.H. (Eds), Springer handbook of microscopy</p><p>(pp.229-318). United Kingdom: Springer.</p><p></p><p>Espinosa, M., Giamperetti, S., Abril, M., & Seijo, A. (2014). Vertical transmission of</p><p>dengue virus in Aedes aegypti collected in Puerto Iguaz, Misiones,</p><p>Argentina. Revista do Instituto de Medicina Tropical de So Paulo, 56(2), 165-</p><p>167.</p><p></p><p>Ferreira-de-Lima, V. H., & Lima-Camara, T. N. (2018). Natural vertical transmission</p><p>of dengue virus in Aedes aegypti and Aedes albopictus: a systematic</p><p>review. Parasites & Vectors, 11(1), 1-8.</p><p></p><p>Fernando, H. S. D., Saavedra-Rodriguez, K., Perera, R., Black, W. C., & De Silva, B.</p><p>N. K. (2020). Resistance to commonly used insecticides and underlying</p><p>mechanisms of resistance in Aedes aegypti (L.) from Sri Lanka. Parasites &</p><p>Vectors, 13(1), 1-14.</p><p></p><p>Fillinger, U., & Lindsay, S. W. (2011). Larval source management for malaria control</p><p>in Africa: myths and reality. Malaria Journal, 10(1), 1-10.</p><p></p><p>Finney, D. J. (1952). Probit analysis: a statistical treatment of the sigmoid response</p><p>curve. Cambridge, UK: Cambridge University Press.</p><p></p><p>Foster, L.E. (2006). Nanotechnology: Science, innovation and oppurtunity. New Jersey,</p><p>Prentice Hall PTR.</p><p></p><p>Foster, W. A., & Walker, E. D. (2019). Mosquitoes (Culicidae). In Mullen, D.R. &</p><p>Durden, L.A. (Eds), Medical and Veterinary Entomology (3rd ed.) (pp. 261-</p><p>325). Academic press.</p><p></p><p>Fradin, M. S. (1998). Mosquitoes and mosquito repellents: a clinician's guide. Annals</p><p>of Internal Medicine, 128(11), 931-940.</p><p></p><p>Killeen, G. F., Fillinger, U., & Knols, B. G. (2002). Advantages of larval control for</p><p>African malaria vectors: low mobility and behavioural responsiveness of</p><p>immature mosquito stages allow high effective coverage. Malaria Journal, 1(1),</p><p>1-7.</p><p></p><p>Gabbott, P. (Ed.). (2008). Principles and applications of thermal analysis. Oxford, UK:</p><p>Blackwell Publishing Ltd.</p><p></p><p>Ganguly, M., & Pramanik, D. (2017). Pectin coated iron oxide nanocomposite-a vehicle</p><p>for controlled release of curcumin. International Journal of Biology and</p><p>Biomedical Engineering, 11, 143-160.</p><p></p><p>Garcez, W. S., Garcez, F. R., da Silva, L. M., & Sarmento, U. C. (2013). Substncias</p><p>de origem vegetal com atividade larvicida contra Aedes aegypti. Revista Virtual</p><p>de Qumica, 5(3), 363-393.</p><p></p><p>Ghibaudo, F., Gerbino, E., Copello, G. J., Dall'Orto, V. C., & Gmez-Zavaglia, A.</p><p>(2019). Pectin-decorated magnetite nanoparticles as both iron delivery systems</p><p>and protective matrices for probiotic bacteria. Colloids and Surfaces B:</p><p>Biointerfaces, 180, 193-201.</p><p></p><p>Gong, X., Peng, S., Wen, W., Sheng, P., & Li, W. (2009). Design and fabrication of</p><p>magnetically functionalized core/shell microspheres for smart drug</p><p>delivery. Advanced Functional Materials, 19(2), 292-297.</p><p></p><p>Gubler, D. J. (2011). Dengue, urbanization and globalization: the unholy trinity of the</p><p>21st century. Tropical Medicine and Health, 39(supplement), S3-S11.</p><p></p><p>Griffiths, P.R. & De Haseth, J.A. (2007). Fourier transform infrared spectroscopy (2nd</p><p>ed.) New York, USA: John Wiley & Sons Ltd.</p><p></p><p>Gnther, H. (2013). NMR spectroscopy: basic principles, concepts and applications in</p><p>chemistry (3rd ed.). Weinheim, Germany:John Wiley & Sons.</p><p></p><p>Guo, J., Giusti, M. M., & Kaletun, G. (2018). Encapsulation of purple corn and</p><p>blueberry extracts in alginate-pectin hydrogel particles: Impact of processing</p><p>and storage parameters on encapsulation efficiency. Food Research</p><p>International, 107, 414-422.</p><p></p><p>Gupta, V. K., Agarwal, S., Asif, M., Fakhri, A., & Sadeghi, N. (2017). Application of</p><p>response surface methodology to optimize the adsorption performance of a</p><p>magnetic graphene oxide nanocomposite adsorbent for removal of methadone</p><p>from the environment. Journal of Colloid and Interface Science, 497, 193-200.</p><p></p><p>Hadjipanayis, G.C. & Siegel R.W. (2012) Nanophase materials: Synthesis, properties,</p><p>applications. London, UK: Kluwer Academic Publishers (Original work</p><p>published 1994).</p><p></p><p>Harrington, L. C., Edman, J. D., & Scott, T. W. (2001). Why do female Aedes aegypti</p><p>(Diptera: Culicidae) feed preferentially and frequently on human</p><p>blood?. Journal of Medical Entomology, 38(3), 411-422.</p><p></p><p>Hoel, D. F., Kline, D. L., & Allan, S. A. (2009). Evaluation of six mosquito traps for</p><p>collection of Aedes albopictus and associated mosquito species in a suburban</p><p>setting in north central Florida1. Journal of the American Mosquito Control</p><p>Association, 25(1), 47-57.</p><p></p><p>Hull, B., Tikasingh, E., de Souza, M., & Martinez, R. (1984). Natural transovarial</p><p>transmission of dengue 4 virus in Aedes aegypti in Trinidad. The American</p><p>Journal of Tropical Medicine and Hygiene, 33(6), 1248-1250.</p><p></p><p>Hussien, N. A., Iklan, N., & Trk, M. (2018). Aptamer-functionalized magnetic</p><p>graphene oxide nanocarrier for targeted drug delivery of paclitaxel. Materials</p><p>Chemistry and Physics, 211, 479-488.</p><p></p><p>Ibaez-Justicia, A., Gloria-Soria, A., Den Hartog, W., Dik, M., Jacobs, F., & Stroo, A.</p><p>(2017). The first detected airline introductions of yellow fever mosquitoes</p><p>(Aedes aegypti) to Europe, at Schiphol International airport, the</p><p>Netherlands. Parasites & Vectors, 10(1), 1-9.</p><p></p><p>Iklan, N., & Polat, S. (2020). Synthesis and characterization of thermo/pH-sensitive</p><p>pectin-graft-poly (dimethylaminoethyl methacrylate) coated magnetic</p><p>nanoparticles. International Journal of Biological Macromolecules, 164, 4499-</p><p>4515.</p><p></p><p>Islam, J., Zaman, K., Duarah, S., Raju, P. S., & Chattopadhyay, P. (2017). Mosquito</p><p>repellents: an insight into the chronological perspectives and novel</p><p>discoveries. Acta tropica, 167, 216-230.</p><p></p><p>Kaleka, A.S.., Kaur, N. & Bali G.K.. (2019). Larval development and moulting. In</p><p>Mikkola, H.(Ed.) Ediible insects London, UK: IntechOpen.</p><p></p><p>Kausar, M. A. (2018). A review on Respiratory allergy caused by</p><p>insects. Bioinformation, 14(9), 540.</p><p></p><p>Keyse, R.J., Garratt-Reed, A.J., Goodhew, P.J. & Lorimer, G.W. (2018). Introduction</p><p>to scanning transmission electron microscopy. Bournmouth, UK: Taylor &</p><p>Francis.</p><p></p><p>Kelly, D. W. (2001). Why are some people bitten more than others?. Trends in</p><p>Parasitology, 17(12), 578-581.</p><p></p><p>Khin, M. M., & Than, K. A. (1983). Transovarial transmission of dengue 2 virus by</p><p>Aedes aegypti in nature. The American Journal of Tropical Medicine and</p><p>Hygiene, 32(3), 590-594.</p><p></p><p>Khursheed, A. (2011). Scanning electron microscope optics and spectrometers.</p><p>Danvers, Massachusettes: World Scientific Publishing Pte. Ltd.</p><p></p><p>Kodoth, A. K., Ghate, V. M., Lewis, S. A., Prakash, B., & Badalamoole, V. (2019).</p><p>Pectin-based silver nanocomposite film for transdermal delivery of</p><p>Donepezil. International Journal of Biological Macromolecules, 134, 269-279.</p><p></p><p>Koenraadt, C. J. M., & Harrington, L. C. (2008). Flushing effect of rain on containerinhabiting</p><p>mosquitoes Aedes aegypti and Culex pipiens (Diptera:</p><p>Culicidae). Journal of Medical Entomology, 45(1), 28-35.</p><p></p><p>Kow, C. Y., Koon, L. L., & Yin, P. F. (2001). Detection of dengue viruses in field</p><p>caught male Aedes aegypti and Aedes albopictus (Diptera: Culicidae) in</p><p>Singapore by type-specific PCR. Journal of Medical Entomology, 38(4), 475-</p><p>479.</p><p></p><p>Kumar, S., & Kumari, R. (2019). Cinnamomum: Review article of essential oil</p><p>compounds, ethnobotany, antifungal and antibacterial effects. Open Access J.</p><p>Sci, 3, 13-16.</p><p></p><p>Kumari, P., Ghosh, B., & Biswas, S. (2016). Nanocarriers for cancer-targeted drug</p><p>delivery. Journal of Drug Targeting, 24(3), 179-191.</p><p></p><p>Lau, S. M. (2018). Combination of gravid ovipositing sticky trap and NS1 antigen test:</p><p>New paradigm for dengue vector surveillance in Selangor Malaysia/Lau Sai</p><p>Ming (Doctoral dissertation). University of Malaya, Kuala Lumpur..</p><p></p><p>Lee, H. L., & Rohani, A. (2005). Transovarial transmission of dengue virus in Aedes</p><p>aegypti and Aedes albopictus in relation to dengue outbreak in an urban area in</p><p>Malaysia. Retrieved from https://apps.who.int/iris/bitstream/handle/</p><p>10665/164121/dbv29p106.pdf</p><p></p><p>Lee, M. (2017). X-ray diffraction for materials research: From fundamentals to</p><p>applications. New York: CRC Press.</p><p></p><p>Leong, C. S., Vythilingam, I., Wong, M. L., Sulaiman, W. Y. W., & Lau, Y. L. (2018).</p><p>Aedes aegypti (Linnaeus) larvae from dengue outbreak areas in Selangor</p><p>showing resistance to pyrethroids but susceptible to organophosphates. Acta</p><p>Tropica, 185, 115-126.</p><p></p><p>Li, C. F., Lim, T. W., Han, L. L., & Fang, R. (1985). Rainfall, abundance of Aedes</p><p>aegypti and dengue infection in Selangor, Malaysia. The Southeast Asian</p><p>Journal Of Tropical Medicine and Public Health, 16(4), 560-568.</p><p></p><p>Li, Y. Q., Kong, D. X., & Wu, H. (2013). Analysis and evaluation of essential oil</p><p>components of cinnamon barks using GCMS and FTIR</p><p>spectroscopy. Industrial Crops and Products, 41, 269-278.</p><p></p><p>Li, Y., Zhao, H., Duan, L. R., Li, H., Yang, Q., Tu, H. H., ... & Wang, S. W. (2014).</p><p>Preparation, characterization and evaluation of bufalin liposomes coated with</p><p>citrus pectin. Colloids and Surfaces A: Physicochemical and Engineering</p><p>Aspects, 444, 54-62.</p><p></p><p>Limkittikul, K., Brett, J., & L'Azou, M. (2014). Epidemiological trends of dengue</p><p>disease in Thailand (20002011): a systematic literature review. PLoS</p><p>Neglected Tropical Diseases, 8(11), e3241.</p><p></p><p>Liptaj, T., Remko, M., & Polin, J. (1980). Analysis of 1 H-NMR spectra of</p><p>cinnamaldehyde type model substances of lignin. Collection of Czechoslovak</p><p>Chemical Communications, 45(2), 330-334.</p><p></p><p>Lfgren, C., & Hermansson, A. M. (2007). Synergistic rheological behaviour of mixed</p><p>HM/LM pectin gels. Food Hydrocolloids, 21(3), 480-486.</p><p></p><p>Loh, K. P., Bao, Q., Ang, P. K., & Yang, J. (2010). The chemistry of graphene. Journal</p><p>of Materials Chemistry, 20(12), 2277-2289.</p><p></p><p>Lucia, A., Toloza, A. C., Guzmn, E., Ortega, F., & Rubio, R. G. (2017). Novel</p><p>polymeric micelles for insect pest control: encapsulation of essential oil</p><p>monoterpenes inside a triblock copolymer shell for head lice control. PeerJ, 5,</p><p>e3171.</p><p></p><p>Magro, M., Bramuzzo, S., Baratella, D., Ugolotti, J., Zoppellaro, G., Chemello,</p><p>G.,Olivotto, I., Ballarin, C., Radaelli, G, Arcaro, B., De, Liguoro,M.,</p><p>Compellotti, O., Guidolin, L., de Almeida Roger, J., Bonaiuto, E. , Zobril.R. &</p><p>Vianello, F. (2019). Self-assembly of chlorin-e6 on -Fe2O3 nanoparticles:</p><p>Application for larvicidal activity against Aedes aegypti. Journal of</p><p>Photochemistry and Photobiology B: Biology, 194, 21-31.</p><p></p><p>Malaysian Meteorlogical Department. (2019) Annual report 2019. Retrieved from</p><p>https://www.met.gov.my/content/pdf/penerbitan/laporantahunan/laporantahun</p><p>an2019.pdf.</p><p></p><p>Mamaghani,R. K., Naghib, S. M., Zahedi, A., Kalkhoran, K. A. H., & Rahmanian, M.</p><p>(2018). Fast synthesis of methacrylated graphene oxide: a graphenefunctionalised</p><p>nanostructure. Micro & Nano Letters, 13(2), 195-197.</p><p></p><p>Mariappan, T., Thenmozhi, V., Udayakumar, P., Bhavaniumadevi, V., & Tyagi, B. K.</p><p>(2015). An observation on breeding behaviour of three different vector species</p><p>(Aedes aegypti Linnaeus 1762, Anopheles stephensi Liston 1901 and Culex</p><p>quinquefasciatus Say 1823) in wells in the coastal region of Ramanathapuram</p><p>district, Tamil Nadu, India. International Journal of Mosquito Research, 2(2),</p><p>42-4.</p><p></p><p>Marcano, D. C., Kosynkin, D. V., Berlin, J. M., Sinitskii, A., Sun, Z., Slesarev, A.,</p><p>Alemany, L.B. Lu, W. & Tour, J. M. (2010). Improved synthesis of graphene</p><p>oxide. ACS Nano, 4(8), 4806-4814.</p><p></p><p>Ministry of Health Malaysia (2021). idengue untuk komuniti versi 3.0. Retrieved from</p><p>https://idengue.mysa.gov.my/</p><p></p><p>Minkin, V.I., Osipov, O.A. & Zhdanov, Y.A. (2012). Dipole moments in organic</p><p>chemistry. New York-London, Springer (Original work published 1970).</p><p></p><p>Mohd-Zaki, A. H., Brett, J., Ismail, E., & L'Azou, M. (2014). Epidemiology of dengue</p><p>disease in Malaysia (20002012): a systematic literature review. PLoS</p><p>Neglected Tropical Diseases, 8(11), e3159.</p><p></p><p>Molhotra, B.D. & Ali, M.A. (2018). Nanomaterials in biosensors: Fundamentals and</p><p>applications. Amsterdam: Elsevier.</p><p></p><p>Molnar, C., & Gair, J. (2013). Sensory Processes. In Concepts of Biology-1st Canadian</p><p>Edition. Retrieved from https://ecampusontario.pressbooks.pub/biology/</p><p>chapter/17-1-sensory-processes.</p><p></p><p>Moore, E. (2016). Fourier transform infrared spectroscopy (FTIR): methods, analysis,</p><p>and research insight. New York, USA: Nova Science Publisher</p><p></p><p>Mordue, A. J., & Blackwell, A. (1993). Azadirachtin: an update. Journal of Insect</p><p>Physiology, 39(11), 903-924.</p><p></p><p>Mudin, R. N. (2015). Dengue incidence and the prevention and control program in</p><p>Malaysia. IIUM Medical Journal Malaysia, 14(1).</p><p></p><p>Muir, L. E., Thorne, M. J., & Kay, B. H. (1992). Aedes aegypti (Diptera: Culicidae)</p><p>vision: spectral sensitivity and other perceptual parameters of the female</p><p>eye. Journal of Medical Entomology, 29(2), 278-281.</p><p></p><p>Mukherjee, B., Satapathy, B. S., Bhattacharya, S., Chakraborty, R., & Mishra, V. P.</p><p>(2017). Pharmacokinetic and pharmacodynamic modulations of therapeutically</p><p>active constituents from orally administered nanocarriers along with a glimpse</p><p>of their advantages and limitations. In Grumezescu, A.M.(Ed) Nano-and</p><p>Microscale Drug Delivery Systems (pp. 357-375). Amsterdam: Elsevier.</p><p></p><p>Mulyatno, K. C., Yamanaka, A., Yotopranoto, S., & Konishi, E. (2012). Vertical</p><p>transmission of dengue virus in Aedes aegypti collected in Surabaya, Indonesia,</p><p>during 20082011. Japanese Journal of Infectious Diseases, 65(3), 274-276.</p><p></p><p>Mun, S., Kim, H. C., Yadave, M., & Kim, J. (2015). Graphene oxidegellan gum</p><p>sodium alginate nanocomposites: synthesis, characterization, and mechanical</p><p>behavior. Composite Interfaces, 22(4), 249-263.</p><p></p><p>Mura, S., Nicolas, J., & Couvreur, P. (2013). Stimuli-responsive nanocarriers for drug</p><p>delivery. Nature Materials, 12(11), 991-1003.</p><p></p><p>Murugesan, A., & Manoharan, M. (2020). Dengue virus. In Ennaji, M.M.</p><p>(Ed.), Emerging and Reemerging Viral Pathogens (pp. 281-359). Cambridge,</p><p>Massachusetts: Academic Press.</p><p></p><p>Muthusamy, R., & Shivakumar, M. S. (2015). Susceptibility status of Aedes aegypti</p><p>(L.)(Diptera: Culicidae) to temephos from three districts of Tamil Nadu,</p><p>India. Journal of Vector Borne Diseases, 52(2), 159.</p><p></p><p>Nadrowski, B., Effertz, T., Senthilan, P. R., & Gpfert, M. C. (2011). Antennal hearing</p><p>in insectsnew findings, new questions. Hearing Research, 273(1-2), 7-13.</p><p></p><p>Ngenefeme, F. T. J., Eko, N. J., Mbom, Y. D., Tantoh, N. D., & Rui, K. W. (2013). A</p><p>one pot green synthesis and characterisation of iron oxide-pectin hybrid</p><p>nanocomposite.Open Journal of Composite Materials, 2013 (30), 30-37.</p><p></p><p>Ngoemazong, E.D., Christiaens, S., Shpigelman, A., Van Loey, A. & Hendrickx, M.</p><p>(2015). The emulsifying and emulsion-stabilizing properties of pectin: a review.</p><p>Comprehensive Reviews in Food Science and Food Safety (14): 705-718.</p><p></p><p>Nussinovitch, A. (2012). Hydrocolloid application: Gum technology in the food and</p><p>other industry. United Kingdom: Springer Science and Business Media.</p><p></p><p>Ooi, P. K., Ching, C. G., Ahmad, M. A., Ng, S. S., Abdullah, M. J., Hassan, H., &</p><p>Hassan, Z. (2014). Characterizations of cupric oxide thin films on glass and</p><p>silicon substrates by radio frequency magnetron sputtering. Sains</p><p>Malaysiana, 43(4), 617-621.</p><p></p><p>Olano, V. A., Matiz, M. I., Lenhart, A., Cabezas, L., Vargas, S. L., Jaramillo, J. F.,</p><p>Sarmiento, D., Alexander, N., Stemstrm, T.A. & Overgaard, H. J. (2015).</p><p>Schools as potential risk sites for vector-borne disease transmission: Mosquito</p><p>vectors in rural schools in two municipalities in Colombia. Journal of the</p><p>American Mosquito Control Association, 31(3), 212-222.</p><p></p><p>Ong, S. Q. (2016). Dengue vector control in Malaysia: A review for current and</p><p>alternative strategies. Sains Malays, 45(5), 777-785.</p><p></p><p>Organisation for Economic Co-operation and Development (OECD). (2018a).</p><p>Consensus document on the biology of mosquito Aedes aegypti. Retrieved from</p><p>https://www.oecd.org/officialdocuments/publicdisplaydocumentpdf/?cote=EN</p><p>V/JM/MONO(2018)23&docLanguage=En</p><p></p><p>Organisation for Economic Co-operation and Development (OECD). (2018b).</p><p>Reproductive biology of the mosquito Ae. aegypti. In Safety assessment of</p><p>transgenic organisms in the environment volume 8 (pp. 49-68). Paris:</p><p>Organisation for Economic Co-operation and Development.</p><p></p><p>Osanloo, M., Amani, A., Sereshti, H., Abai, M. R., Esmaeili, F., & Sedaghat, M. M.</p><p>(2017). Preparation and optimization nanoemulsion of Tarragon (Artemisia</p><p>dracunculus) essential oil as effective herbal larvicide against Anopheles</p><p>stephensi. Industrial Crops and Products, 109, 214-219.</p><p></p><p>Packard, R. M. (2016). A history of global health: Interventions into the lives of other</p><p>peoples (pp. 227-266). Baltimore: John Hopkins University Press,</p><p></p><p>Paredes, J. I., Villar-Rodil, S., Martinez-Alonso, A., & Tascon, J. M. D. (2008).</p><p>Graphene oxide dispersions in organic solvents. Langmuir, 24(19), 10560-</p><p>10564.</p><p></p><p>Patel, S., Bajpai, J., Saini, R., Bajpai, A. K., & Acharya, S. (2018). Sustained release of</p><p>pesticide (Cypermethrin) from nanocarriers: an effective technique for</p><p>environmental and crop protection. Process Safety and Environmental</p><p>Protection, 117, 315-325.</p><p></p><p>Patra, J. K., Das, G., Fraceto, L. F., Campos, E. V. R., del Pilar Rodriguez-Torres, M.,</p><p>Acosta-Torres, L. S., Diaz-Torrez, L.A. Grillo, R., Swarmy, M.K. Sharma,S,</p><p>Habtemariam, S.. & Shin, H. S. (2018). Nano based drug delivery systems:</p><p>recent developments and future prospects. Journal of</p><p>Nanobiotechnology, 16(1), 1-33.</p><p></p><p>Paupy, C., Le Goff, G., Brengues, C., Guerra, M., Revollo, J., Simon, Z. B., Herv, J.P.</p><p>& Fontenille, D. (2012). Genetic structure and phylogeography of Aedes</p><p>aegypti, the dengue and yellow-fever mosquito vector in Bolivia. Infection,</p><p>Genetics and Evolution, 12(6), 1260-1269.</p><p></p><p>Pavaloiu, R. D., Fawzia, S., Bubueanu, C., Georgetaneagu, A. A., Hlevca, C., &</p><p>Nechifor, G. (2018). Release of Polyphenols from Liposomes Loaded with</p><p>Echinacea purpurea. Revista De Chimie, 69(9), 2315-2317.</p><p></p><p>Paz-Cedeno, F. R., Carceller, J. M., Iborra, S., Donato, R. K., Godoy, A. P., de Paula,</p><p>A. V., Monti, R. Corma, A. & Masarin, F. (2021). Magnetic graphene oxide as</p><p>a platform for the immobilization of cellulases and xylanases: Ultrastructural</p><p>characterization and assessment of lignocellulosic biomass</p><p>hydrolysis. Renewable Energy, 164, 491-501.</p><p></p><p>Pennycook, S.J. & Nellist, P.D. (2011). Scanning transmission electron microscopy:</p><p>Imaging and analysis. New York: Springer.</p><p></p><p>Petaling Jaya City Council (2021). Background. Retrieved from</p><p>https://www.mbpj.gov.my/en/mbpj/profile/background</p><p></p><p>Piacentini, E. (2016). Encapsulation efficiency. Encyclopedia of membranes, 706-707.</p><p></p><p>Pradhan, B., Behera, C., Nayak. R. & Jena, M. (2020). Use of phytochemicals:A</p><p>promising and eco-friendly approach for the management of mosquito vector</p><p>populations. In Barik, T.K. (Ed.) Molecular identification of mosquito vectors</p><p>and their management (pp.51-88).Singapore: Springer Nature Singapore Pte.</p><p>Ltd.</p><p></p><p>Rayegan, A., Allafchian, A., Sarsari, I. A., & Kameli, P. (2018). Synthesis and</p><p>characterization of basil seed mucilage coated Fe3O4 magnetic nanoparticles as</p><p>a drug carrier for the controlled delivery of cephalexin. International Journal of</p><p>Biological Macromolecules, 113, 317-328.</p><p></p><p>Rios, F. J., Moustad-Moussa, N., & Martins, J. O. (2018). Interplay between hormones,</p><p>the immune system, and metabolic disorders. Retrieved from</p><p>https://www.hindawi.com/journals/mi/2018/8654212/</p><p></p><p>Ritger, P. L., & Peppas, N. A. (1987). A simple equation for description of solute</p><p>release II. Fickian and anomalous release from swellable devices. Journal of</p><p>Controlled Release, 5(1), 37-42.</p><p></p><p>Rivera-Prez, C., Clifton, M. E., & Noriega, F. G. (2017). How micronutrients</p><p>influence the physiology of mosquitoes. Current Opinion in Insect Science, 23,</p><p>112-117.</p><p></p><p>Robinson, J,W., Frame, E.M.S. & Frame, G.M. (2004). Undergraduate instrumental</p><p>analysis (6th ed.). New York: CRC Press.</p><p></p><p>Rohani, A., Zamree, I., Joseph, R. T., & Lee, H. L. (2008). Persistency of transovarial</p><p>dengue virus in Aedes aegypti (Linn.). The Southeast Asian Journal of Tropical</p><p>Medicine and Public Health, 39(5), 813-816.</p><p></p><p>Rosen, L., Shroyer, D. A., Tesh, R. B., Freier, J. E., & Lien, J. C. (1983). Transovarial</p><p>transmission of dengue viruses by mosquitoes: Aedes albopictus and Aedes</p><p>aegypti. The American Journal Of Tropical Medicine And Hygiene, 32(5),</p><p>1108-1119.</p><p></p><p>Ross, P. A., Ritchie, S. A., Axford, J. K., & Hoffmann, A. A. (2019). Loss of</p><p>cytoplasmic incompatibility in Wolbachia-infected Aedes aegypti under field</p><p>conditions. PLoS Neglected Tropical Diseases, 13(4), e0007357.</p><p></p><p>Saleem, M. A., & Lobanova, I. (2020). Mosquito-borne diseases. In Qureshi, A.A. &</p><p>Saeed, O. (Eds), Dengue Virus Disease (pp. 57-83). Cambridge, Massachusetts:</p><p>Academic Press.</p><p></p><p>Samuel, M. S., , N. P. (2018). Adsorption of Pb (II) from aqueous solution using a</p><p>magnetic chitosan/graphene oxide composite and its toxicity</p><p>studies. International Journal of Biological Macromolecules, 115, 1142-1150.</p><p></p><p>Sarwar, M. (2020). Typical flies: Natural history, lifestyle and diversity of Diptera.</p><p>In Life Cycle and Development of Diptera (pp. 1-50). London, UK: IntechOpen.</p><p></p><p>Seenuvasan, M., Malar, C. G., Preethi, S., Balaji, N., Iyyappan, J., Kumar, M. A., &</p><p>Kumar, K. S. (2013). Fabrication, characterization and application of pectin</p><p>degrading Fe3O4SiO2 nanobiocatalyst. Materials Science and Engineering:</p><p>C, 33(4), 2273-2279.</p><p></p><p>Sherlala, A. I. A., Raman, A. A. A., Bello, M. M., & Buthiyappan, A. (2019).</p><p>Adsorption of arsenic using chitosan magnetic graphene oxide</p><p>nanocomposite. Journal of Environmental Management, 246, 547-556.</p><p></p><p>Shirinova, H., Palma, L. D., & Sarasini, F. , Tirill, J., Ramazanov, M.A., Hajiyeva, F.</p><p>Sannino, D., Polichetti, M. & Galluzzi, A.(2016). Synthesis and</p><p>characterization of magnetic nanocomposites for environmental</p><p>remediation. Chemical Engineering, 47.</p><p></p><p>Simi, A., Sokovi, M. D., Risti, M., GrujiJovanovi, S., Vukojevi, J., & Marin, P.</p><p>D. (2004). The chemical composition of some Lauraceae essential oils and their</p><p>antifungal activities. Phytotherapy Research: An International Journal Devoted</p><p>to Pharmacological and Toxicological Evaluation of Natural Product</p><p>Derivatives, 18(9), 713-717.</p><p></p><p>Singh, R., & Lillard Jr, J. W. (2009). Nanoparticle-based targeted drug</p><p>delivery. Experimental and Molecular Pathology, 86(3), 215-223.</p><p></p><p>Singh, Y., Meher, J. G., Raval, K., Khan, F. A., Chaurasia, M., Jain, N. K., & Chourasia,</p><p>M. K. (2017). Nanoemulsion: Concepts, development and applications in drug</p><p>delivery. Journal of Controlled Release, 252, 28-49.</p><p></p><p>Skae, F. M. T. (1902). Dengue fever in Penang. British Medical Journal, 2(2185), 1581.</p><p></p><p>Skoog, D. A., Holler, F. J., & Crouch, S. R. (2017). Principles of instrumental analysis</p><p>(7th ed.). Boston, Massachusettes: Cengage learning.</p><p></p><p>Snow, G. E., Haaland, B., Ooi, E. E., & Gubler, D. J. (2014). Research on dengue during</p><p>World War II revisited. The American Journal of Tropical Medicine and</p><p>hygiene, 91(6), 1203.</p><p></p><p>Stoller-Conrad, J. (2015). Mosquito use smell to see their hosts. Retrieved from</p><p>https://www.caltech.edu/about/news/mosquitoes-use-smell-see-their-hosts-</p><p>47338</p><p></p><p>Suh, E., Bohbot, J. D., & Zwiebel, L. J. (2014). Peripheral olfactory signaling in</p><p>insects. Current Opinion in Insect Science, 6, 86-92.</p><p></p><p>Sun, C., Lee, J. S., & Zhang, M. (2008). Magnetic nanoparticles in MR imaging and</p><p>drug delivery. Advanced Drug Delivery Reviews, 60(11), 1252-1265.</p><p></p><p>Sun, Q., Li, J., Sun, Y., Chen, Q., Zhang, L., & Le, T. (2020). The antifungal effects of</p><p>cinnamaldehyde against Aspergillus niger and its application in bread</p><p>preservation. Food Chemistry, 317, 126405.</p><p></p><p>Sundar Raj, A. A., Rubila, S., Jayabalan, R., & Ranganathan, T. V. (2012). A review</p><p>on pectin: chemistry due to general properties of pectin and its pharmaceutical</p><p>uses.Open Access Scientific Reports, 1(12), 1-4.</p><p></p><p>Supramaniam, J., Adnan, R., Kaus, N. H. M., & Bushra, R. (2018). Magnetic</p><p>nanocellulose alginate hydrogel beads as potential drug delivery</p><p>system. International Journal of Biological Macromolecules, 118, 640-648.</p><p></p><p>Sworn, G. & Stouby, L. (2009) Gellan gum. In Phillips, G.O. & Willams, P.A. (Eds)</p><p>Handbooks of hydrocolloids (3rd ed.) (pp. 855-885). United Kingdom: Elsevier.</p><p></p><p>Tavares, M., da Silva, M. R. M., de Siqueira, L. B. D. O., Rodrigues, R. A. S., Bodjolled'Almeida,</p><p>L., Dos Santos, E. P., & Ricci-Jnior, E. (2018). Trends in insect</p><p>repellent formulations: a review. International Journal of</p><p>Pharmaceutics, 539(1-2), 190-209.</p><p></p><p>Tee, H. P., How, S. H., Jamalludin, A. R., Safhan, M. N., Sapian, M. M., Kuan, Y. C.,</p><p>& Sapari, S. (2009). Risk factors associated with development of dengue</p><p>haemorrhagic fever or dengue shock syndrome in adults in Hospital Tengku</p><p>Ampuan Afzan Kuantan. The Medical Journal of Malaysia, 64(4), 316-320.</p><p></p><p>Thavara, U., Tawatsin, A., Kong-Ngamsuk, W., & Mulla, M. (2004). Efficacy and</p><p>longevity of a new formulation of temephos larvicide tested in village-scale</p><p>trials against larval aedes aegypti tn water-storage containers. Journal of the</p><p>American Mosquito Control Association, 20(2):176-182.</p><p></p><p>Tolle, M. A. (2009). Mosquito-borne diseases. Current problems in Pediatric and</p><p>Adolescent Health Care, 39(4), 97-140.</p><p></p><p>Tomasko, S., Flashinski, R. A., & Pellitteri, P. (2007). Wisconsin pesticide applicator</p><p>training manual: Commercial cateogry 7.1. Madison, Wisconsin: Division of</p><p>Cooperative Extension of the University of Wisconsin--Extension</p><p></p><p>Trivedi, V. (2019). Chemical bonding for JEE Main & Advanced, NEET, 2nd edition.</p><p>New Delhi: Disha Publication.</p><p></p><p>Tu, J., Boyle, A. L., Friedrich, H., Bomans, P. H., Bussmann, J., Sommerdijk, N.</p><p>A.,Jiskoot, W. & Kros, A. mesoporous silica nanoparticles with large pores for</p><p>the encapsulation and release of proteins. ACS Material Interfaces, 8(47),</p><p>32211-32219.</p><p></p><p>Tuiskunen, B. A., & Lundkvist, . (2013). Dengue virusesan overview. Infection</p><p>Ecology & Epidemiology, 3(1), 19839.</p><p></p><p>Tyagi, B.K. (2004). The invicible deadly mosquitoes: India's health and economy</p><p>enemy#1. Jodhpur, India: Pawan Kumar Scientific Publishers (India).</p><p></p><p>Ul-Hamid, A. (2018). A beginners' guide to scanning electron microscopy . Asterdam:</p><p>Springer International Publishing.</p><p></p><p>United States Environment Protection Agency (EPA). (n.d.). Mosquito life cycle.</p><p>Retrieved from https://www.epa.gov/mosquitocontrol/mosquito-life-cycle</p><p></p><p>United Nations for the Humanitarian Affairs (OCHA). (2019). Malaria: Half of the</p><p>World's population is at risk and climate change threatens to expand its reach.</p><p>Retrieved from https://reliefweb.int/report/world/malaria-half-world-spopulation-</p><p>risk-and-climate-change-threatens-expand-its-reach</p><p></p><p>Uno, N., & Ross, T. M. (2018). Dengue virus and the host innate immune</p><p>response. Emerging Microbes & Infections, 7(1), 1-11.</p><p></p><p>Webster, B., & Card, R. T. (2017). Use of habitat odour by hostseeking</p><p>insects. Biological Reviews, 92(2), 1241-1249.</p><p></p><p>Widawati, M., & Riandi, M. U. (2013). The effectiveness of citronella</p><p>(cymbopogonnardus l.) microcapsules as larvicides against aedes aegypti larvae.</p><p>In International Seminar Integrated Vector Management, UNDIP. Retrieved</p><p>from https://www.researchgate.net/profile/Mutiara-Widawati/publication/</p><p>264159775_THE_EFFECTIVENESS_OF_CITRONELLA_Cymbopogonnard</p><p>us_L_MICROCAPSULES_AS_LARVICIDES_AGAINST_Aedes_aegypti_L</p><p>ARVAE/links/53d087ca0cf2f7e53cfb8026/THE-EFFECTIVENESS-OFCITRONELLA-</p><p>Cymbopogonnardus-L-MICROCAPSULES-ASLARVICIDES-</p><p>AGAINST-Aedes-aegypti-LARVAE.pdf</p><p></p><p>World Health Organization (WHO). (1990). Environmental health criteria 94:</p><p>Pemethrin. Retrieved from https://apps.who.int/iris/bitstream/handle/10665/</p><p>38949/9241542942-eng.pdf?sequence=1&isAllowed=y</p><p></p><p>World Health Organization (WHO). (2004). Permethrin in drinking-water:</p><p>Background document for development of WHO guidelines for drinking-water</p><p>quality. Retrieved from http://apps.who.int/iris/bitstream/handle/10665/75377/</p><p>WHO_SDE_WSH_03.04_111_eng.pdf;jsessionid=66157889CEFA370A413E</p><p>85698A52641B?sequence=1</p><p></p><p>World Health Organization (WHO). (2011). Comprehensive guidelines for prevention</p><p>and control of dengue and dengue haemorrhagic fever: Revised and expanded</p><p>edition. New Delhi, India: World Health Organization.</p><p></p><p>World Health Organization (WHO). (2012). Global strategy for dengue prevention and</p><p>control 2012-2020. Retrieved from https://www.who.int/immunization/</p><p>sage/meetings/2013/april/5_Dengue_SAGE_Apr2013_Global_Strategy.pdf</p><p></p><p>World Health Organization (WHO). (2018). World Malaria Report 2018. Retrieved</p><p>from http://apps.who.int/iris/bitstream/handle/10665/275867/9789241565653-</p><p>eng.pdf?ua=1</p><p></p><p>World Health Organization (WHO). (2021). Dengue Situation Update Report Number</p><p>615. Retrieved from https://apps.who.int/iris/bitstream/handle/10665/341149/</p><p>Dengue-20210311.pdf?sequence=5&isAllowed=y</p><p></p><p>Vasantha-Srinivasan, P., Senthil-Nathan, S., Ponsankar, A., Thanigaivel, A., Edwin, E.</p><p>S., Selin-Rani, S., Chellappadian, M., Pradeepa, V., Lija-Escaline, J., Kalaivani,</p><p>K., Hunter, W.B., Duraipandiyan, V. & Al-Dhabi, N. A. (2017). Comparative</p><p>analysis of mosquito (Diptera: Culicidae: Aedes aegypti Liston) responses to the</p><p>insecticide Temephos and plant derived essential oil derived from Piper betle</p><p>L. Ecotoxicology and Environmental Safety, 139, 439-446.</p><p></p><p>Vashist, A., Kaushik, A., Vashist, A., Jayant, R. D., Tomitaka, A., Ahmad, S., Gupta,</p><p>Y.K. & Nair, M. (2016). Recent trends on hydrogel based drug delivery systems</p><p>for infectious diseases. Biomaterials Science, 4(11), 1535-1553.</p><p></p><p>Vinauger, C., Van Breugel, F., Locke, L. T., Tobin, K. K., Dickinson, M. H., Fairhall,</p><p>A. L., Akbari O.S., & Riffell, J. A. (2019). Visual-olfactory integration in the</p><p>human disease vector mosquito Aedes aegypti. Current Biology, 29(15), 2509-</p><p>2516.</p><p></p><p>Wang, S. Y., Chen, P. F., & Chang, S. T. (2005). Antifungal activities of essential oils</p><p>and their constituents from indigenous cinnamon (Cinnamomum osmophloeum)</p><p>leaves against wood decay fungi. Bioresource Technology, 96(7), 813-818.</p><p></p><p>Xia, Q., Li, L., & Zhao, L. (2017). Silica nanoparticle-based dual-responsive</p><p>nanoprodrug system for liver cancer therapy. Experimental and therapeutic</p><p>medicine, 14(3), 2071-2077.</p><p></p><p>Xu, Y., & Shi, G. (2011). Assembly of chemically modified graphene: methods and</p><p>applications. Journal of Materials Chemistry, 21(10), 3311-3323.</p><p></p><p>Yoder, C.H. (2006). Ionic compounds: Applications of chemistry to mineralogy.</p><p>Canada: John Wiley & Sons. Inc.</p><p></p><p>Yu, C. Y., Cao, H., Zhang, X. C., Zhou, F. Z., Cheng, S. X., Zhang, X. Z., & Zhuo, R.</p><p>X. (2009). Hybrid nanospheres and vesicles based on pectin as drug</p><p>carriers. Langmuir, 25(19), 11720-11726.</p><p></p><p>Zhang, H., Han, X., Yang, Z., Zou, J., & Tang, H. (2013). Enhanced Adsorption of</p><p>Methylene Blue on Graphene Oxide by Tuning the Oxidation Degree of</p><p>Graphene Oxide. Journal of Nanomaterials & Molecular Nanotechnology S1:</p><p>003. of, 6, 2.</p><p></p><p>Zhao, F., Zhang, B., & Feng, L. (2012). Preparation and magnetic properties of</p><p>magnetite nanoparticles. Materials Letters, 68, 112-114.</p><p></p><p>Zhu, Y., Murali, S., Cai, W., Li, X., Suk, J. W., Potts, J. R., & Ruoff, R. S. (2010).</p><p>Graphene and graphene oxide: synthesis, properties, and</p><p>applications. Advanced Materials, 22(35), 3906-3924.</p><p></p><p>Zhu, W., Wu, J., Guo, X., Sun, X., Li, Q., Wang, J., & Chen, L. (2020). Development</p><p>and physicochemical characterization of chitosan hydrochloride/sulfobutyl</p><p>ethercyclodextrin nanoparticles for cinnamaldehyde entrapment. Journal of</p><p>Food Biochemistry, 44(6), e13197.</p><p></p><p>Zohreh, N., Hosseini, S. H., & Pourjavadi, A. (2016). Hydrazine-modified starch coated</p><p>magnetic nanoparticles as an effective pH-responsive nanocarrier for</p><p>doxorubicin delivery. Journal of Industrial and Engineering Chemistry, 39,</p><p>203-209.</p><p></p>