Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE)

Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE)

<p>This study aims to identify the essential oils composition, phytochemicals, and</p><p>antioxidant activity of Syzygium pyrifolium (Blume) DC. leaves and bark extracts. The</p><p>essential oils were obtained using hydrodistillat...

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Main Author: Nur Hazwanie Abdul Kadir
Format: thesis
Language:eng
Published: 2022
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QD Chemistry
Online Access:https://ir.upsi.edu.my/detailsg.php?det=9754
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institution Universiti Pendidikan Sultan Idris
collection UPSI Digital Repository
language eng
topic QD Chemistry
spellingShingle QD Chemistry
Nur Hazwanie Abdul Kadir
Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE)
description <p>This study aims to identify the essential oils composition, phytochemicals, and</p><p>antioxidant activity of Syzygium pyrifolium (Blume) DC. leaves and bark extracts. The</p><p>essential oils were obtained using hydrodistillation technique and their chemical</p><p>compositions were determined by gas chromatography and gas chromatography-mass</p><p>spectrometry. Phytochemicals were separated using various chromatography</p><p>techniques and their structures were elucidated using infrared, nuclear magnetic</p><p>resonance, ultraviolet, and mass spectrometry. Antioxidant activity of the essential</p><p>oils, extracts, and selected phytochemicals was determined using the total phenolic</p><p>content and free radical scavenging assay. Results showed that S. pyrifolium leaf oil</p><p>mainly consists of geraniol (73.8%), -pinene (7.0%), -pinene (5.7%), and (E)--</p><p>ocimene (4.5%). Geraniol was successfully separated from the leaf oil as a pure</p><p>compound. The bark oil contains cuparene (7.2%), -elemene (6.8%), longifolene</p><p>(5.6%) and -terpineol (4.7%) as major components. Seven compounds were also</p><p>separated from the leaf and bark extracts of S. pyrifolium and successfully identified</p><p>as 5-hydroxy-3,7,4-trimethoxyflavone, 5-hydroxy-3,7,3,4-tetramethoxyflavone, 5,4-</p><p>dihydroxy-3,7,3-trimethoxyflavone, 5-hydroxy-6,7,4-trimethoxyflavone, 4,5,7-</p><p>trimethoxyflavone, 5,7-dimethoxyflavone, and 3,4,5-trihydroxybenzoic acid. The bark</p><p>methanolic extract exhibited the highest total phenolic content with gallic acid</p><p>equivalent to 490 mg/g extract. Meanwhile, leaf and bark methanolic extracts showed</p><p>strong antioxidant activity in the free radical scavenging assay with percentage</p><p>inhibition of 88.4% and 89.9%, respectively. In conclusion, leaf and bark oils of S.</p><p>pyrifolium consist of oxygenated monoterpenes and sesquiterpene hydrocarbons as</p><p>major group components. In addition, leaves and bark methanolic extracts mainly</p><p>contain flavonoids and phenolic compounds which exhibited strong antioxidant</p><p>activity. This study implies that extracts of S. pyrifolium have potential to prevent free</p><p>radical harmful effects and may protect against various cardiovascular and</p><p>inflammatory diseases.</p>
format thesis
qualification_name
qualification_level Master's degree
author Nur Hazwanie Abdul Kadir
author_facet Nur Hazwanie Abdul Kadir
author_sort Nur Hazwanie Abdul Kadir
title Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE)
title_short Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE)
title_full Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE)
title_fullStr Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE)
title_full_unstemmed Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE)
title_sort essential oils, phytochemistry and antioxidant activity of syzygium pyrifolium (blume) dc. (myrtaceae)
granting_institution Universiti Pendidikan Sultan Idris
granting_department Fakulti Sains dan Matematik
publishDate 2022
url https://ir.upsi.edu.my/detailsg.php?det=9754
_version_ 1794025740281315328
spelling oai:ir.upsi.edu.my:97542023-12-11 Essential oils, phytochemistry and antioxidant activity of Syzygium pyrifolium (Blume) DC. (MYRTACEAE) 2022 Nur Hazwanie Abdul Kadir QD Chemistry <p>This study aims to identify the essential oils composition, phytochemicals, and</p><p>antioxidant activity of Syzygium pyrifolium (Blume) DC. leaves and bark extracts. The</p><p>essential oils were obtained using hydrodistillation technique and their chemical</p><p>compositions were determined by gas chromatography and gas chromatography-mass</p><p>spectrometry. Phytochemicals were separated using various chromatography</p><p>techniques and their structures were elucidated using infrared, nuclear magnetic</p><p>resonance, ultraviolet, and mass spectrometry. Antioxidant activity of the essential</p><p>oils, extracts, and selected phytochemicals was determined using the total phenolic</p><p>content and free radical scavenging assay. Results showed that S. pyrifolium leaf oil</p><p>mainly consists of geraniol (73.8%), -pinene (7.0%), -pinene (5.7%), and (E)--</p><p>ocimene (4.5%). Geraniol was successfully separated from the leaf oil as a pure</p><p>compound. The bark oil contains cuparene (7.2%), -elemene (6.8%), longifolene</p><p>(5.6%) and -terpineol (4.7%) as major components. Seven compounds were also</p><p>separated from the leaf and bark extracts of S. pyrifolium and successfully identified</p><p>as 5-hydroxy-3,7,4-trimethoxyflavone, 5-hydroxy-3,7,3,4-tetramethoxyflavone, 5,4-</p><p>dihydroxy-3,7,3-trimethoxyflavone, 5-hydroxy-6,7,4-trimethoxyflavone, 4,5,7-</p><p>trimethoxyflavone, 5,7-dimethoxyflavone, and 3,4,5-trihydroxybenzoic acid. The bark</p><p>methanolic extract exhibited the highest total phenolic content with gallic acid</p><p>equivalent to 490 mg/g extract. Meanwhile, leaf and bark methanolic extracts showed</p><p>strong antioxidant activity in the free radical scavenging assay with percentage</p><p>inhibition of 88.4% and 89.9%, respectively. In conclusion, leaf and bark oils of S.</p><p>pyrifolium consist of oxygenated monoterpenes and sesquiterpene hydrocarbons as</p><p>major group components. In addition, leaves and bark methanolic extracts mainly</p><p>contain flavonoids and phenolic compounds which exhibited strong antioxidant</p><p>activity. This study implies that extracts of S. pyrifolium have potential to prevent free</p><p>radical harmful effects and may protect against various cardiovascular and</p><p>inflammatory diseases.</p> 2022 thesis https://ir.upsi.edu.my/detailsg.php?det=9754 https://ir.upsi.edu.my/detailsg.php?det=9754 text eng closedAccess Masters Universiti Pendidikan Sultan Idris Fakulti Sains dan Matematik <p>Abdelgaleil, S.A.M., Badawy, M.E.I., Shawir, M.S. & Mohamed, M.I.E. (2015). 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