Identification of the cellular origin and "stemness" phenotype of malignant rhabdoid tumours (MRT) may represent a new therapeutic approach in paediatric oncology
introduction: Malignant Rhabdoid Tumours (MRT) arc especially lethal cancers that predominantly occur in infants and young ehildrcn. MRT arc caused by biallelic inactivation of a single gene; SMARCB I which is a component of SWI/S F chromatin remodelling complex. The tumours can be found almost ever...
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