Lapatinib induced-changes in Caco-2 intestinal monolayer via ErbB1 inhibition / Raja Nur Firzanah Syaza Raja Sharin
Lapatinib (LAP) is an orally administered dual ErbBl and ErbB2 tyrosine kinase inhibitor for ErbB2-positive breast tumours, but is associated with diarrhoea. Incidence of lapatinib-induced diarrhoea (LID) is as high as 58-78% in treated patients. Although short-term diarrhoea is tolerable, prolonged...
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| Format: | Thesis |
| Language: | English |
| Published: |
2023
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| Online Access: | https://ir.uitm.edu.my/id/eprint/91425/1/91425.pdf |
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