Abrogation of oncogenic k-ras function by andrographolide derivatives via in silico, in vitro, and in vivo approaches

Abrogation of oncogenic k-ras function by andrographolide derivatives via in silico, in vitro, and in vivo approaches

The rat sarcoma (Ras) proteins are small guanosine triphosphatases (GTPases) that act as molecular switches in major signalling pathways involved in cell proliferation, differentiation, and survival, such as mitogenactivated protein kinase (MAPK) and phosphatidylinositol 3-kinase (PI3K) cascades...

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书目详细资料
主要作者:	Quah, Shun Ying
格式:	Thesis
语言:	English
出版:	2021
主题:	Neoplasms - therapy
在线阅读:	http://psasir.upm.edu.my/id/eprint/97712/1/FPSK%28p%29%202021%2015%20-%20IR.1.pdf
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